Studies into hormonal imprinting in a Tetrahymena thermophila mutant incapable of lysosomal enzyme secretion.

P. Kovacs, Y. Banno, Y. Nozawa, G. Csaba

Research output: Contribution to journalArticle

Abstract

Reexposure to insulin after primary interaction (hormonal imprinting) was followed by a binding increase in T. pyriformis and by a binding decrease in T. thermophila. The sec. mutant, MS-1 strain of T. thermophila, which is unable of lysosomal enzyme secretion, also showed a binding increase on a second exposure to insulin, from which it follows that alteration of the enzyme secretion, or other factors associated with mutation, accounted for reversion of the trend of imprinting. Thyrotropic hormone (TSH) also gave rise to a negative imprinting in T. thermophila, but did not alter the binding relations of the MS-1 mutant strain.

Original languageEnglish
Pages (from-to)293-296
Number of pages4
JournalCellular and molecular biology
Volume35
Issue number3
Publication statusPublished - Jan 1 1989

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ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

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