Strukturális MR-vizsgálat szkizofréniában optimalizált voxel-alapú morfometriával.

Translated title of the contribution: Structural MRI investigation in schizophrenia with optimised voxel-based morphometry--a pilot study

Adám Feldmann, N. Kovács, Kövér Ferenc, T. Tényi, S. Fekete, Herold Róbert

Research output: Contribution to journalArticle

Abstract

The quantitative and structural MRI methods have an emergent role in the fields of psychiatric disorders. In our paper we present voxel-based morphometry, which is the most frequently used structural MRI method. We compared eight patients with schizophrenia and eight, age-matched healthy subjects to detect focal tissue differences in gray and white matter, and cerebrospinal fluids between the two groups. As with earlier studies, patients with schizophrenia showed decreased gray matter tissue density in frontotemporal and insular regions bilaterally. Moreover, the left-sided parietal operculum and the calcarina showed focal decrease in tissue density. Density decrease in the frontotemporal and insular white matter was detected bilaterally, which was similar to gray matter changes. The left sided precuneus and lingual gyrus were also involved in reduced white matter density. Increased cerebrospinal fluid spaces were detected in the frontal regions and the ventricles. Our results with the optimised voxel-based morphometry are in line with earlier imaging studies and correspond with neuropsychological detectable frontotemporal deficits in schizophrenia.

Original languageHungarian
Pages (from-to)456-461
Number of pages6
JournalPsychiatria Hungarica : A Magyar Pszichiátriai Társaság tudományos folyóirata
Volume22
Issue number6
Publication statusPublished - 2007

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Schizophrenia
Cerebrospinal Fluid
Occipital Lobe
Parietal Lobe
Psychiatry
Healthy Volunteers
White Matter
Gray Matter

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Strukturális MR-vizsgálat szkizofréniában optimalizált voxel-alapú morfometriával. / Feldmann, Adám; Kovács, N.; Ferenc, Kövér; Tényi, T.; Fekete, S.; Róbert, Herold.

In: Psychiatria Hungarica : A Magyar Pszichiátriai Társaság tudományos folyóirata, Vol. 22, No. 6, 2007, p. 456-461.

Research output: Contribution to journalArticle

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