Structural and functional analysis of the scute locus in Drosophila melanogaster

D. P. Furman, S. Rodin, V. A. Ratner

Research output: Contribution to journalArticle

Abstract

The functional expression of 12 scute alleles in homozygotes and compounds of Drosophila melanogaster at 14°, 22°, 30°C is analysed. Based on the data obtained, linear maps for bristles and mutations are built. The basic features of the maps, clustering and polarity, are invariable with respect to temperature, scute gene dosage and cross direction. In addition local dominance of the norm over bristle reduction was produced by the scute mutation; different types of complementation reactions were established for each bristle. The gene scute is treated as an operon-like system, composed of 3-4 cistrons with each controlling the formation of bristles on a particular region of the fly's body. This model argues well with the structure of maps constructed and implies a post-translational level of initial events of bristle-formation process.

Original languageEnglish
Pages (from-to)231-238
Number of pages8
JournalTheoretical And Applied Genetics
Volume55
Issue number5
DOIs
Publication statusPublished - Sep 1979

Fingerprint

setae (animal)
Drosophila melanogaster
Body Regions
Mutation
loci
Gene Dosage
Homozygote
Operon
Diptera
Genes
Cluster Analysis
Alleles
Temperature
mutation
gene dosage
operon
homozygosity
dominance (genetics)
genes
alleles

Keywords

  • Drosophila melanogaster
  • Maps
  • Operon-like model
  • Scute locus

ASJC Scopus subject areas

  • Genetics(clinical)
  • Genetics
  • Plant Science
  • Horticulture
  • Agronomy and Crop Science

Cite this

Structural and functional analysis of the scute locus in Drosophila melanogaster. / Furman, D. P.; Rodin, S.; Ratner, V. A.

In: Theoretical And Applied Genetics, Vol. 55, No. 5, 09.1979, p. 231-238.

Research output: Contribution to journalArticle

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