Structural analysis of w/o/w multiple emulsions by means of DSC

Anita Kovács, I. Csóka, Magdolna Kónya, E. Csányi, A. Fehér, I. Erös

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The properties of the inner and the external aqueous phases, were studied in w/o/w multiple emulsions with light microscopic image analysis and differential scanning calorimetry (DSC). The importance of multiple emulsions lies in the presence of these aqueous phases, making them available for sustained, controlled drug delivery systems. Differentiation of these two aqueous phases, studying the effect of manufacturing technology on droplet structure, quantitative determination of phase volumes and any changes occurring during storage are essential when planning w/o/w emulsions. The present study uses microscopic observations combined with DSC measurements in order to identify the formed structure, at developmental stage in case of different components, preparation methods, and stirring rates. These tools are beneficial during manufacturing as in process controls, or to ensure product quality.

Original languageEnglish
Pages (from-to)491-497
Number of pages7
JournalJournal of Thermal Analysis and Calorimetry
Volume82
Issue number2
DOIs
Publication statusPublished - Nov 2005

Fingerprint

Emulsions
structural analysis
Structural analysis
emulsions
Differential scanning calorimetry
heat measurement
scanning
manufacturing
Controlled drug delivery
stirring
image analysis
Image analysis
Process control
planning
delivery
drugs
Planning
preparation
products

Keywords

  • Different polarity oils
  • Droplet size analysis
  • DSC
  • Formulation
  • w/o/w multiple emulsions

ASJC Scopus subject areas

  • Chemical Engineering(all)

Cite this

Structural analysis of w/o/w multiple emulsions by means of DSC. / Kovács, Anita; Csóka, I.; Kónya, Magdolna; Csányi, E.; Fehér, A.; Erös, I.

In: Journal of Thermal Analysis and Calorimetry, Vol. 82, No. 2, 11.2005, p. 491-497.

Research output: Contribution to journalArticle

Kovács, Anita ; Csóka, I. ; Kónya, Magdolna ; Csányi, E. ; Fehér, A. ; Erös, I. / Structural analysis of w/o/w multiple emulsions by means of DSC. In: Journal of Thermal Analysis and Calorimetry. 2005 ; Vol. 82, No. 2. pp. 491-497.
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