Stressor-specific increase of vasopressin mRNA in paraventricular hypophysiotrophic neurons

Viktor Bartanusz, Jean Michel Aubry, Thierry Steimer, Judit Baffi, J. Kiss

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Cellular levels of vasopressin (VP) and corticotropin-releasing factor (CRF) RNA transcripts were determined in hypophysiotrophic neurons after open-field and immobilization stress using quantitative in situ hybridization. We found that 8 min open-field stress is sufficient to produce a significant up-regulation of CRF mRNA, without any concomitant changes in the level of VP mRNA. In contrast, 8 min immobilization stress resulted in an increased labeling density of both CRF and VP mRNAs. These results suggest that the level of CRF and VP transcripts in parvicellular hypophysiotrophic neurons is differentially regulated in a stressor-specific manner.

Original languageEnglish
Pages (from-to)35-38
Number of pages4
JournalNeuroscience Letters
Volume170
Issue number1
DOIs
Publication statusPublished - Mar 28 1994

Fingerprint

Corticotropin-Releasing Hormone
Vasopressins
Neurons
Messenger RNA
Immobilization
In Situ Hybridization
Up-Regulation
RNA

Keywords

  • CRF
  • Hypothalamic paraventricular nucleus
  • Immobilization
  • In situ hybridization
  • mRNA
  • Open-field
  • Stress
  • Vasopressin

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Stressor-specific increase of vasopressin mRNA in paraventricular hypophysiotrophic neurons. / Bartanusz, Viktor; Aubry, Jean Michel; Steimer, Thierry; Baffi, Judit; Kiss, J.

In: Neuroscience Letters, Vol. 170, No. 1, 28.03.1994, p. 35-38.

Research output: Contribution to journalArticle

Bartanusz, Viktor ; Aubry, Jean Michel ; Steimer, Thierry ; Baffi, Judit ; Kiss, J. / Stressor-specific increase of vasopressin mRNA in paraventricular hypophysiotrophic neurons. In: Neuroscience Letters. 1994 ; Vol. 170, No. 1. pp. 35-38.
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