Stress-related changes of opiate sensitivity in thermoregulation

G. Benedek, Margit Szikszay, F. Obál

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Body temperature reactions to morphine were tested in freely-moving adult rats reared without any previous experience to human handling. These animals reacted to 8 mg/kg morphine s.c. with a biphasic hypo-hyperthermic response. When the rats had been handled for six days, the same dose of morphine induced a monophasic hyperthermic reaction. The results are regarded as evidence that stress-related factors interfere with the thermo-regulatory effects of morphine.

Original languageEnglish
Pages (from-to)591-593
Number of pages3
JournalLife Sciences
Volume33
Issue numberSUPPL. 1
DOIs
Publication statusPublished - 1983

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Opiate Alkaloids
Body Temperature Regulation
Morphine
Rats
Body Temperature
Animals

ASJC Scopus subject areas

  • Pharmacology

Cite this

Stress-related changes of opiate sensitivity in thermoregulation. / Benedek, G.; Szikszay, Margit; Obál, F.

In: Life Sciences, Vol. 33, No. SUPPL. 1, 1983, p. 591-593.

Research output: Contribution to journalArticle

Benedek, G. ; Szikszay, Margit ; Obál, F. / Stress-related changes of opiate sensitivity in thermoregulation. In: Life Sciences. 1983 ; Vol. 33, No. SUPPL. 1. pp. 591-593.
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