Stressz fehérjék az orvostudományban.

Translated title of the contribution: Stress proteins in medicine

P. Csermely, J. Somogyi

Research output: Contribution to journalArticle

Abstract

The stress, or heat-shock proteins are essential for the homeostasis of living cells. Their role in the intracellular transport, refolding, or elimination of proteins becomes especially important after any unusual stimuli (stress) of the cell. This central role explains why stress proteins represent one of the most conservative structures of living cells. Human and bacterial stress proteins also show a homology as high, as 50%. This structural similarity links the immune responses against bacterial infections with a number of autoimmune diseases, such as lupus erythematosus, rheumatoid arthritis and insulin dependent diabetes mellitus, IDDM. In the end of our review we also discuss the possible role of stress proteins in protection against cardiac ischaemia and their putative role in aging.

Original languageHungarian
Pages (from-to)1347-1351
Number of pages5
JournalOrvosi Hetilap
Volume133
Issue number22
Publication statusPublished - May 31 1992

Fingerprint

Heat-Shock Proteins
Medicine
Type 1 Diabetes Mellitus
Bacterial Proteins
Bacterial Infections
Autoimmune Diseases
Rheumatoid Arthritis
Homeostasis
Ischemia
Proteins

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Csermely, P., & Somogyi, J. (1992). Stressz fehérjék az orvostudományban. Orvosi Hetilap, 133(22), 1347-1351.

Stressz fehérjék az orvostudományban. / Csermely, P.; Somogyi, J.

In: Orvosi Hetilap, Vol. 133, No. 22, 31.05.1992, p. 1347-1351.

Research output: Contribution to journalArticle

Csermely, P & Somogyi, J 1992, 'Stressz fehérjék az orvostudományban.', Orvosi Hetilap, vol. 133, no. 22, pp. 1347-1351.
Csermely P, Somogyi J. Stressz fehérjék az orvostudományban. Orvosi Hetilap. 1992 May 31;133(22):1347-1351.
Csermely, P. ; Somogyi, J. / Stressz fehérjék az orvostudományban. In: Orvosi Hetilap. 1992 ; Vol. 133, No. 22. pp. 1347-1351.
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