Stress induced ACTH release after removal of the hypothalamus in rats with atrophied neural lobe

J. Marton, E. Stark, G. Makara, M. Palkóvits

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Twenty-four hr after isolation of the pituitary by surgical removal of the medial hypothalamus, i.e., in rats with pituitary island, E. coli endotoxin significantly increased the plasma corticosterone level. Atrophy of the neural lobe, due to pituitary stalk section performed one month prior to removal of the medial hypothalamus, did not prevent the inrease of ACTH relese by E. coli endotoxin. E. coli endotoxin-induced ACTH release in MBH-deprived animals does not appear to be a function of mechanisms operating only in the innervated lobe.

Original languageEnglish
Pages (from-to)247-251
Number of pages5
JournalActa Physiologica Academiae Scientiarum Hungaricae
Volume46
Issue number3
Publication statusPublished - 1975

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Posterior Pituitary Gland
Endotoxins
Adrenocorticotropic Hormone
Hypothalamus
Middle Hypothalamus
Escherichia coli
Pituitary Gland
Corticosterone
Islands
Atrophy

ASJC Scopus subject areas

  • Physiology

Cite this

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abstract = "Twenty-four hr after isolation of the pituitary by surgical removal of the medial hypothalamus, i.e., in rats with pituitary island, E. coli endotoxin significantly increased the plasma corticosterone level. Atrophy of the neural lobe, due to pituitary stalk section performed one month prior to removal of the medial hypothalamus, did not prevent the inrease of ACTH relese by E. coli endotoxin. E. coli endotoxin-induced ACTH release in MBH-deprived animals does not appear to be a function of mechanisms operating only in the innervated lobe.",
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