Strategic Application of Residence-Time Control in Continuous-Flow Reactors

I. Mándity, Sándor B. Ötvös, F. Fülöp

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

As a sustainable alternative for conventional batch-based synthetic techniques, the concept of continuous-flow processing has emerged in the synthesis of fine chemicals. Systematic tuning of the residence time, a key parameter of continuous-reaction technology, can govern the outcome of a chemical reaction by determining the reaction rate and the conversion and by influencing the product selectivity. This review furnishes a brief insight into flow reactions in which high chemo- and/or stereoselectivity can be attained by strategic residence-time control and illustrates the importance of the residence time as a crucial parameter in sustainable method development. Such a fine reaction control cannot be performed in conventional batch reaction set-ups.

Original languageEnglish
Pages (from-to)212-223
Number of pages12
JournalChemistryOpen
Volume4
Issue number3
DOIs
Publication statusPublished - Jun 1 2015

Fingerprint

Stereoselectivity
Reaction rates
Chemical reactions
Tuning
Processing

Keywords

  • chemoselectivity
  • continuous flow
  • diastereoselectivity
  • reactors
  • residence time

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Strategic Application of Residence-Time Control in Continuous-Flow Reactors. / Mándity, I.; Ötvös, Sándor B.; Fülöp, F.

In: ChemistryOpen, Vol. 4, No. 3, 01.06.2015, p. 212-223.

Research output: Contribution to journalArticle

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