Stochastic analysis of the parity-violating energy differences between enantiomers and its implications for the origin of biological chirality

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Abstract

A stochastic description of a racemic mixture is developed taking into account the slight energy difference between enantiomers originating from parity violation (ΔEpv ≈ 10-13 Jmol-1). The system can be described by an asymmetric binomial distribution. A method is developed to calculate the probability of forming the more-stable isomer in excess, which is not significantly larger than 50% under normal conditions. It is concluded that the parity-violating energy difference between enantiomers is very unlikely to be relevant in considerations about the origin of biological chirality.

Original languageEnglish
Pages (from-to)12711-12713
Number of pages3
JournalJournal of Physical Chemistry A
Volume110
Issue number47
DOIs
Publication statusPublished - Nov 30 2006

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Enantiomers
Chirality
enantiomers
chirality
parity
Isomers
isomers
energy

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry

Cite this

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abstract = "A stochastic description of a racemic mixture is developed taking into account the slight energy difference between enantiomers originating from parity violation (ΔEpv ≈ 10-13 Jmol-1). The system can be described by an asymmetric binomial distribution. A method is developed to calculate the probability of forming the more-stable isomer in excess, which is not significantly larger than 50{\%} under normal conditions. It is concluded that the parity-violating energy difference between enantiomers is very unlikely to be relevant in considerations about the origin of biological chirality.",
author = "G. Lente",
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AB - A stochastic description of a racemic mixture is developed taking into account the slight energy difference between enantiomers originating from parity violation (ΔEpv ≈ 10-13 Jmol-1). The system can be described by an asymmetric binomial distribution. A method is developed to calculate the probability of forming the more-stable isomer in excess, which is not significantly larger than 50% under normal conditions. It is concluded that the parity-violating energy difference between enantiomers is very unlikely to be relevant in considerations about the origin of biological chirality.

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