Stimulus-secretion coupling and mitochondrial metabolism in steroid-secreting cells

A. Spät, János G. Pitter, Tibor Rohács, György Szabadkai

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Ca2+ signal in high-Ca2+ perimitochondrial microdomains is amplified within the mitochondrial matrix and activates Ca2+-dependent dehydrogenases. In steroid-secreting cells, small cytoplasmic Ca2+ signals may also augment mitochondrial Ca2+ concentration. The ensuing formation of NADH and NADPH may have an essential role in supporting the increased steroid secretion.

Original languageEnglish
Pages (from-to)197-200
Number of pages4
JournalNews in Physiological Sciences
Volume16
Issue number5
Publication statusPublished - Oct 2001

Fingerprint

Steroids
NADP
NAD
Oxidoreductases

ASJC Scopus subject areas

  • Physiology

Cite this

Stimulus-secretion coupling and mitochondrial metabolism in steroid-secreting cells. / Spät, A.; Pitter, János G.; Rohács, Tibor; Szabadkai, György.

In: News in Physiological Sciences, Vol. 16, No. 5, 10.2001, p. 197-200.

Research output: Contribution to journalArticle

Spät, A. ; Pitter, János G. ; Rohács, Tibor ; Szabadkai, György. / Stimulus-secretion coupling and mitochondrial metabolism in steroid-secreting cells. In: News in Physiological Sciences. 2001 ; Vol. 16, No. 5. pp. 197-200.
@article{ffa835d157014c1ca20bdd9372d23efd,
title = "Stimulus-secretion coupling and mitochondrial metabolism in steroid-secreting cells",
abstract = "Ca2+ signal in high-Ca2+ perimitochondrial microdomains is amplified within the mitochondrial matrix and activates Ca2+-dependent dehydrogenases. In steroid-secreting cells, small cytoplasmic Ca2+ signals may also augment mitochondrial Ca2+ concentration. The ensuing formation of NADH and NADPH may have an essential role in supporting the increased steroid secretion.",
author = "A. Sp{\"a}t and Pitter, {J{\'a}nos G.} and Tibor Roh{\'a}cs and Gy{\"o}rgy Szabadkai",
year = "2001",
month = "10",
language = "English",
volume = "16",
pages = "197--200",
journal = "Physiology",
issn = "1548-9213",
publisher = "American Physiological Society",
number = "5",

}

TY - JOUR

T1 - Stimulus-secretion coupling and mitochondrial metabolism in steroid-secreting cells

AU - Spät, A.

AU - Pitter, János G.

AU - Rohács, Tibor

AU - Szabadkai, György

PY - 2001/10

Y1 - 2001/10

N2 - Ca2+ signal in high-Ca2+ perimitochondrial microdomains is amplified within the mitochondrial matrix and activates Ca2+-dependent dehydrogenases. In steroid-secreting cells, small cytoplasmic Ca2+ signals may also augment mitochondrial Ca2+ concentration. The ensuing formation of NADH and NADPH may have an essential role in supporting the increased steroid secretion.

AB - Ca2+ signal in high-Ca2+ perimitochondrial microdomains is amplified within the mitochondrial matrix and activates Ca2+-dependent dehydrogenases. In steroid-secreting cells, small cytoplasmic Ca2+ signals may also augment mitochondrial Ca2+ concentration. The ensuing formation of NADH and NADPH may have an essential role in supporting the increased steroid secretion.

UR - http://www.scopus.com/inward/record.url?scp=0035490879&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035490879&partnerID=8YFLogxK

M3 - Article

C2 - 11572920

AN - SCOPUS:0035490879

VL - 16

SP - 197

EP - 200

JO - Physiology

JF - Physiology

SN - 1548-9213

IS - 5

ER -