Stimulating effect of triiodothyronine on cell-mediated immunity

C. Balázs, A. Leövey, M. Szabó, G. Bakó

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

The effects in vitro and in vivo of triiodothyronine on certain functions of human lymphocytes and polymorphonuclear granulocytes have been investigated. Triiodothyronine was able to enhance the phagocytic capacity and chemiluminescent activity of polymorphonuclear granulocytes. PHA-P-induced3H-thymidine incorporation into lymphocytes was significantly increased in the presence of triiodothyronine. A concentration-dependent enhancing effect of triiodothyronine on antibody-dependent enhancing effect of triiodothyronine on antibody-dependent cell-mediated cytotoxicity was also observed.

Original languageEnglish
Pages (from-to)19-23
Number of pages5
JournalEuropean Journal of Clinical Pharmacology
Volume17
Issue number1
DOIs
Publication statusPublished - Jan 1980

Fingerprint

Triiodothyronine
Cellular Immunity
Granulocytes
Lymphocytes
Antibody-Dependent Cell Cytotoxicity
Blocking Antibodies
Thymidine

Keywords

  • antibody-dependent cell-mediated cytotoxicity
  • chemiluminescence
  • Graves' disease
  • lymphocyte transformation
  • phagocytosis
  • triiodothyronine

ASJC Scopus subject areas

  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Pharmacology (medical)

Cite this

Stimulating effect of triiodothyronine on cell-mediated immunity. / Balázs, C.; Leövey, A.; Szabó, M.; Bakó, G.

In: European Journal of Clinical Pharmacology, Vol. 17, No. 1, 01.1980, p. 19-23.

Research output: Contribution to journalArticle

Balázs, C. ; Leövey, A. ; Szabó, M. ; Bakó, G. / Stimulating effect of triiodothyronine on cell-mediated immunity. In: European Journal of Clinical Pharmacology. 1980 ; Vol. 17, No. 1. pp. 19-23.
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