15α‐Hydroxymethyl‐5‐androstene‐3β,16β,17β‐triol (5d) and 16β‐hydroxy‐15α‐(hydroxymethyl)estratriene derivatives 9 were prepared from the corresponding 15‐hydroxymethylene‐16‐ketones 3 and 4. The configurations of the chiral centers were determined by means of chemical transformations and on the basis of spectroscopic data. The D‐seco derivatives 6 and 8 were identified as the products of a fragmentation and a 1,3‐dicarbonyl fission, respectively.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry