Steroids. Part 43.1 Thermal decomposition of steroidal azidoformates

G. Schneider, László Hackler, János Szanyi, P. Sohár

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Abstract

Thermolysis of the four possible isomeric 3-methoxy-16-methylestra-1,3, 5(10)-trien-17-yl azidoformates 1b, 6b, 10b and 14b, of 3-methoxyestra-1,3,5(10) -trien-17β-yl azidoformate 17b, and of 16β-azidoformyloxymethyl-3- methoxyestra-1,3,5(10)-triene 21b was realized at 100°C. Thermolysis results in insertion of the nitrene intermediate into C-H bonds, the site of which depends on the steric position of the substituents in the D ring of the sterane skeleton.

Original languageEnglish
Pages (from-to)37-42
Number of pages6
JournalJournal of the Chemical Society, Perkin Transactions 1
Issue number1
Publication statusPublished - 1991

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Trientine
Thermolysis
Pyrolysis
Steroids
phenylnitrene
3-methoxyestra-1,3,5(10)-triene

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Steroids. Part 43.1 Thermal decomposition of steroidal azidoformates. / Schneider, G.; Hackler, László; Szanyi, János; Sohár, P.

In: Journal of the Chemical Society, Perkin Transactions 1, No. 1, 1991, p. 37-42.

Research output: Contribution to journalArticle

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