Steroid receptor and molecular chaperone encounters in the nucleus.

D. B. DeFranco, P. Csermely

Research output: Contribution to journalReview article

15 Citations (Scopus)

Abstract

Steroid hormone receptors interact with several different molecular chaperones. DeFranco and Csermely discuss how the molecular chaperones p23 and Hsp90 may serve to regulate the activity of the ligand-bound steroid receptors within the nucleus. The authors hypothesize that these chaperone proteins may have a proactive role in promoting recycling of receptors once they have interacted with chromatin and in allowing rebinding of ligand once the receptors have been recycled.

Original languageEnglish
Pages (from-to)PE1
JournalScience's STKE : signal transduction knowledge environment
Volume2000
Issue number42
Publication statusPublished - Jul 25 2000

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Steroid receptor and molecular chaperone encounters in the nucleus.'. Together they form a unique fingerprint.

  • Cite this