Steroid formation in vitro in rabbit ovary

G. Telegdy, K. Savard

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Biosynthesis from acetate-1-14C of 10 steroids has been assessed in vitro by corpora lutea and interstitium of the ovaries from rabbits obtained 6 days after mating. The following steroids were synthesized: 3β-hydroxy-Δ5-pregnen-20-one, progesterone, 20α and 20β-hydroxy-Δ4-pregnen-3-ones, 17-hydroxyprogesterone, dehydroepiandrosterone, Δ4-androstene-3, 17-dione and testosterone; no radioactive estrone or estradiol-17β was found. The most highly radioactive steroids in both tissues were progesterone, pregnenolone and 20α-hydroxy-Δ4-pregnen-3-one. On a per g. basis, corpus luteal tissue incorporated approximately 20 times more radioactivity into 8 steroids than interstitium.

Original languageEnglish
Pages (from-to)685-694
Number of pages10
JournalSteroids
Volume8
Issue number5
Publication statusPublished - Nov 1966

Fingerprint

Ovary
Steroids
Rabbits
Corpus Luteum
Progesterone
Tissue
17-alpha-Hydroxyprogesterone
Pregnenolone
Dehydroepiandrosterone
Androstenedione
Estrone
Biosynthesis
Radioactivity
Testosterone
Estradiol
Acetates
In Vitro Techniques

ASJC Scopus subject areas

  • Molecular Biology
  • Endocrinology
  • Biochemistry

Cite this

Telegdy, G., & Savard, K. (1966). Steroid formation in vitro in rabbit ovary. Steroids, 8(5), 685-694.

Steroid formation in vitro in rabbit ovary. / Telegdy, G.; Savard, K.

In: Steroids, Vol. 8, No. 5, 11.1966, p. 685-694.

Research output: Contribution to journalArticle

Telegdy, G & Savard, K 1966, 'Steroid formation in vitro in rabbit ovary', Steroids, vol. 8, no. 5, pp. 685-694.
Telegdy, G. ; Savard, K. / Steroid formation in vitro in rabbit ovary. In: Steroids. 1966 ; Vol. 8, No. 5. pp. 685-694.
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