Stereospecific one-pot synthesis of a new 6,11-dioxa-7-aza-D-homosteroid ring system

F. Fülöp, G. Bernáth, István Pelczer

Research output: Contribution to journalArticle

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Abstract

(r-7a,t-11a,c-13a)-6,7,7a,8,9,10,11,11a-Octahydro[1,3]benzoxazino [3,4-a] [3,1] benzoxazine (3) was prepared in a one-pot synthesis from trans-2-hydroxymethylcyclohexylamine. 3 was epimerized to 4 (r-7a, t-11a,t-13a), furnishing an equilibrium mixture with 3:4 = 2:1. The stereochemistry of the diastereomers was determined with via DRDS measurements.

Original languageEnglish
Pages (from-to)2517-2518
Number of pages2
JournalTetrahedron Letters
Volume27
Issue number22
DOIs
Publication statusPublished - 1986

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Homosteroids
Benzoxazines
Stereochemistry

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Stereospecific one-pot synthesis of a new 6,11-dioxa-7-aza-D-homosteroid ring system. / Fülöp, F.; Bernáth, G.; Pelczer, István.

In: Tetrahedron Letters, Vol. 27, No. 22, 1986, p. 2517-2518.

Research output: Contribution to journalArticle

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