Structural analogs of swainsonine and castanospermine have been synthesized using [4+2] cycloadditions of chiral azomethines with Danishefsky diene. Similar hydroxyindolizidines were prepared by [3+2] dipolar cycloadditions of sugar derived cyclic nitrones with methyl acrylate. Stereoselectivity of [2+2] photocycloadditions of uridine derivatives was also studied.
ASJC Scopus subject areas
- Chemical Engineering(all)