Stereochemical studies, 1001 1 Part 99/103: A. Kálmán, Gy. Argay, P. Sohár, J. Szabó, L. Fodor, G. Bernáth, J. Mol. Struct., submitted for...

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Abstract

Title full: Stereochemical studies, 1001 1 Part 99/103: A. Kálmán, Gy. Argay, P. Sohár, J. Szabó, L. Fodor, G. Bernáth, J. Mol. Struct., submitted for publication. Part of this work was presented in a lecture by G. Bernáth, F. Fülöp, J. Kóbor, J. Lázár, G. Motika, P. Sohár, Gy. Argay, A. Kálmán at "The Third International Kyoto Conference on New Aspects of Organic Chemistry", November 18-22, 1985, Kyoto, Japan. See: Abstract p. 208.. Saturated heterocycles, 1041. Synthesis, and NMR and X-ray study of 1-substituted azeto[2,1-a]isoquinoline diastereomers1. N→O acyl migration of the N-benzoyl derivatives (4) of 1- [bis(hydroxymethyl)-methyl]-6,7-dimethoxy-1,2,3,4-tetra-hydroisoquinolin e (3a) gave the threo- and erythro-O-benzoyl compounds (6a, 6b), which were converted to cis- and trans-1-hydroxymethyl-1, 4,5,9b-tetrahydro-2H-azeto[2,1-a] isoquinolines (11a, 11b). The structures of the compounds prepared were proved by X-ray diffraction and NMR spectroscopic measurements.

Original languageEnglish
Pages (from-to)5139-5148
Number of pages10
JournalTetrahedron
Volume42
Issue number18
DOIs
Publication statusPublished - 1986

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Isoquinolines
Organic Chemistry
X-Ray Diffraction
Publications
Japan
Nuclear magnetic resonance
X-Rays
Derivatives
X ray diffraction
X rays
isoquinoline

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

@article{f1818155f824454db8b7ba2f9132feaf,
title = "Stereochemical studies, 1001 1 Part 99/103: A. K{\'a}lm{\'a}n, Gy. Argay, P. Soh{\'a}r, J. Szab{\'o}, L. Fodor, G. Bern{\'a}th, J. Mol. Struct., submitted for...",
abstract = "Title full: Stereochemical studies, 1001 1 Part 99/103: A. K{\'a}lm{\'a}n, Gy. Argay, P. Soh{\'a}r, J. Szab{\'o}, L. Fodor, G. Bern{\'a}th, J. Mol. Struct., submitted for publication. Part of this work was presented in a lecture by G. Bern{\'a}th, F. F{\"u}l{\"o}p, J. K{\'o}bor, J. L{\'a}z{\'a}r, G. Motika, P. Soh{\'a}r, Gy. Argay, A. K{\'a}lm{\'a}n at {"}The Third International Kyoto Conference on New Aspects of Organic Chemistry{"}, November 18-22, 1985, Kyoto, Japan. See: Abstract p. 208.. Saturated heterocycles, 1041. Synthesis, and NMR and X-ray study of 1-substituted azeto[2,1-a]isoquinoline diastereomers1. N→O acyl migration of the N-benzoyl derivatives (4) of 1- [bis(hydroxymethyl)-methyl]-6,7-dimethoxy-1,2,3,4-tetra-hydroisoquinolin e (3a) gave the threo- and erythro-O-benzoyl compounds (6a, 6b), which were converted to cis- and trans-1-hydroxymethyl-1, 4,5,9b-tetrahydro-2H-azeto[2,1-a] isoquinolines (11a, 11b). The structures of the compounds prepared were proved by X-ray diffraction and NMR spectroscopic measurements.",
author = "G. Bern{\'a}th and Jen{\'o} K{\'o}bor and F. F{\"u}l{\"o}p and P. Soh{\'a}r and G. Argay and A. K{\'a}lm{\'a}n",
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T2 - A. Kálmán, Gy. Argay, P. Sohár, J. Szabó, L. Fodor, G. Bernáth, J. Mol. Struct., submitted for...

AU - Bernáth, G.

AU - Kóbor, Jenó

AU - Fülöp, F.

AU - Sohár, P.

AU - Argay, G.

AU - Kálmán, A.

PY - 1986

Y1 - 1986

N2 - Title full: Stereochemical studies, 1001 1 Part 99/103: A. Kálmán, Gy. Argay, P. Sohár, J. Szabó, L. Fodor, G. Bernáth, J. Mol. Struct., submitted for publication. Part of this work was presented in a lecture by G. Bernáth, F. Fülöp, J. Kóbor, J. Lázár, G. Motika, P. Sohár, Gy. Argay, A. Kálmán at "The Third International Kyoto Conference on New Aspects of Organic Chemistry", November 18-22, 1985, Kyoto, Japan. See: Abstract p. 208.. Saturated heterocycles, 1041. Synthesis, and NMR and X-ray study of 1-substituted azeto[2,1-a]isoquinoline diastereomers1. N→O acyl migration of the N-benzoyl derivatives (4) of 1- [bis(hydroxymethyl)-methyl]-6,7-dimethoxy-1,2,3,4-tetra-hydroisoquinolin e (3a) gave the threo- and erythro-O-benzoyl compounds (6a, 6b), which were converted to cis- and trans-1-hydroxymethyl-1, 4,5,9b-tetrahydro-2H-azeto[2,1-a] isoquinolines (11a, 11b). The structures of the compounds prepared were proved by X-ray diffraction and NMR spectroscopic measurements.

AB - Title full: Stereochemical studies, 1001 1 Part 99/103: A. Kálmán, Gy. Argay, P. Sohár, J. Szabó, L. Fodor, G. Bernáth, J. Mol. Struct., submitted for publication. Part of this work was presented in a lecture by G. Bernáth, F. Fülöp, J. Kóbor, J. Lázár, G. Motika, P. Sohár, Gy. Argay, A. Kálmán at "The Third International Kyoto Conference on New Aspects of Organic Chemistry", November 18-22, 1985, Kyoto, Japan. See: Abstract p. 208.. Saturated heterocycles, 1041. Synthesis, and NMR and X-ray study of 1-substituted azeto[2,1-a]isoquinoline diastereomers1. N→O acyl migration of the N-benzoyl derivatives (4) of 1- [bis(hydroxymethyl)-methyl]-6,7-dimethoxy-1,2,3,4-tetra-hydroisoquinolin e (3a) gave the threo- and erythro-O-benzoyl compounds (6a, 6b), which were converted to cis- and trans-1-hydroxymethyl-1, 4,5,9b-tetrahydro-2H-azeto[2,1-a] isoquinolines (11a, 11b). The structures of the compounds prepared were proved by X-ray diffraction and NMR spectroscopic measurements.

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