Ossejt-transzplantáció a gyomor-bél rendszer betegségeinek kezelésében

Translated title of the contribution: Stem cell transplantation in the treatment of gastrointestinal diseases

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

The stem cells with self-renewal ability are capable to form one or more cell types. They will be in the target of cell and gene therapy because of their multipotency and easy retrieval. Application of adult mesenchymal, neuronal, epidermal and haematopoietic stem cell can be favourable in the treatment of cardiac (myocardial infarction), bone (osteoarthritis), neurological (Parkinson's, Alzheimer's) and hematological (hemophilia, thrombocytopenia) disorders. Authors summarize the knowledge in connection with their application in the therapy of gastrointestinal diseases. Haematopoietic stem cell transplantation has been successful for the treatment of refractory Crohn's disease, as well as in selected group of celiac patients. Mesenchymal stem cell transplantation has been proved beneficial in the prevention of liver fibrotic process. It will gain more grounds in the treatment of autoimmune liver diseases: autoimmune hepatitis, primary biliary cirrhosis and primary sclerosing cholangitis in the future. Well-designed, multicentric, prospective studies are needed to confirm the results of case reports and clinical studies with small group of patients.

Translated title of the contributionStem cell transplantation in the treatment of gastrointestinal diseases
Original languageHungarian
Pages (from-to)1449-1455
Number of pages7
JournalOrvosi hetilap
Volume149
Issue number31
DOIs
Publication statusPublished - Aug 3 2008

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Stem cell transplantation in the treatment of gastrointestinal diseases'. Together they form a unique fingerprint.

  • Cite this