Statin use and risk of atrial fibrillation or flutter: A population-based case-control study

Giacomo Veronese, Jonathan Montomoli, Morten Schmidt, E. Puhó, Henrik Toft Sørensen

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The pleiotropic effects of statins have been suggested to prevent atrial fibrillation onset. We conducted a population-based case-control study using medical databases from Northern Denmark (population: 1.8 million) to examine the association between statin use and atrial fibrillation or flutter. We identified 51,374 patients with atrial fibrillation or flutter between 1999 and 2010 and 513,670 matched population controls. We collected data on statin prescriptions redeemed within 90 days (current users) or longer (former users) before the diagnosis date of atrial fibrillation or flutter. We stratified statin users by duration of exposure, determined by the number of days between first and last redeemed prescription before the diagnosis date (

Original languageEnglish
Pages (from-to)186-194
Number of pages9
JournalAmerican Journal of Therapeutics
Volume22
Issue number3
DOIs
Publication statusPublished - May 16 2015

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Hydroxymethylglutaryl-CoA Reductase Inhibitors
Atrial Flutter
Atrial Fibrillation
Case-Control Studies
Population
Prescriptions
Population Control
Denmark
Databases

Keywords

  • atrial fibrillation
  • epidemiology
  • prevention
  • statin

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

Cite this

Statin use and risk of atrial fibrillation or flutter : A population-based case-control study. / Veronese, Giacomo; Montomoli, Jonathan; Schmidt, Morten; Puhó, E.; Sørensen, Henrik Toft.

In: American Journal of Therapeutics, Vol. 22, No. 3, 16.05.2015, p. 186-194.

Research output: Contribution to journalArticle

Veronese, Giacomo ; Montomoli, Jonathan ; Schmidt, Morten ; Puhó, E. ; Sørensen, Henrik Toft. / Statin use and risk of atrial fibrillation or flutter : A population-based case-control study. In: American Journal of Therapeutics. 2015 ; Vol. 22, No. 3. pp. 186-194.
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