Abstract
Conventional drug delivery systems have limitations according to their toxicity and poor solubility, bioavailability, stability, and pharmacokinetics (PK). Here, we highlight the importance of functionalized titanate nanotubes (TNTs) as targeted drug delivery systems. We discuss the differences in the physicochemical properties of TNTs and carbon nanotubes (CNTs) and focus on the use of functionalization to improve their characteristics. TNTs are promising materials for drug delivery systems because of their superb properties compared with CNTs, such as their processability, wettability, and biocompatibility. Functionalization improves nanoparticles (NPs) via their surface modification and enables them to achieve the targeted therapy.
| Original language | English |
|---|---|
| Journal | Drug Discovery Today |
| DOIs | |
| Publication status | Published - Jan 1 2019 |
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ASJC Scopus subject areas
- Pharmacology
- Drug Discovery
Cite this
Standpoint on the priority of TNTs and CNTs as targeted drug delivery systems. / Ranjous, Yasmin; Regdon, Géza; Pintye-Hódi, K.; Sovány, Tamás.
In: Drug Discovery Today, 01.01.2019.Research output: Contribution to journal › Short survey
}
TY - JOUR
T1 - Standpoint on the priority of TNTs and CNTs as targeted drug delivery systems
AU - Ranjous, Yasmin
AU - Regdon, Géza
AU - Pintye-Hódi, K.
AU - Sovány, Tamás
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Conventional drug delivery systems have limitations according to their toxicity and poor solubility, bioavailability, stability, and pharmacokinetics (PK). Here, we highlight the importance of functionalized titanate nanotubes (TNTs) as targeted drug delivery systems. We discuss the differences in the physicochemical properties of TNTs and carbon nanotubes (CNTs) and focus on the use of functionalization to improve their characteristics. TNTs are promising materials for drug delivery systems because of their superb properties compared with CNTs, such as their processability, wettability, and biocompatibility. Functionalization improves nanoparticles (NPs) via their surface modification and enables them to achieve the targeted therapy.
AB - Conventional drug delivery systems have limitations according to their toxicity and poor solubility, bioavailability, stability, and pharmacokinetics (PK). Here, we highlight the importance of functionalized titanate nanotubes (TNTs) as targeted drug delivery systems. We discuss the differences in the physicochemical properties of TNTs and carbon nanotubes (CNTs) and focus on the use of functionalization to improve their characteristics. TNTs are promising materials for drug delivery systems because of their superb properties compared with CNTs, such as their processability, wettability, and biocompatibility. Functionalization improves nanoparticles (NPs) via their surface modification and enables them to achieve the targeted therapy.
UR - http://www.scopus.com/inward/record.url?scp=85067247666&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85067247666&partnerID=8YFLogxK
U2 - 10.1016/j.drudis.2019.05.019
DO - 10.1016/j.drudis.2019.05.019
M3 - Short survey
C2 - 31158513
AN - SCOPUS:85067247666
JO - Drug Discovery Today
JF - Drug Discovery Today
SN - 1359-6446
ER -