Stability of cyclophosphamide containing infusions

Andras Mittner, Z. Vincze, K. Jemnitz

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The stability of cyclophosphamide containing Normal Saline admixture solution for infusion at various temperatures has been studied. The difference in stability during storage at room temperature and at 2-8 °C was observed based on an HPLC assay. Stored in a refrigerator, the decomposition of the active agent was less than 1% on the seventh day, and remained under 1.11% on the 14th day. Under room temperature the decomposition exceeded 10% on the seventh day and was over 25% on the 14th day.

Original languageEnglish
Pages (from-to)224-225
Number of pages2
JournalPharmazie
Volume54
Issue number3
Publication statusPublished - 1999

Fingerprint

Cyclophosphamide
Temperature
Decomposition
Refrigerators
Sodium Chloride
Assays
High Pressure Liquid Chromatography

ASJC Scopus subject areas

  • Molecular Medicine
  • Chemistry(all)
  • Organic Chemistry
  • Drug Discovery
  • Pharmaceutical Science
  • Pharmacology

Cite this

Mittner, A., Vincze, Z., & Jemnitz, K. (1999). Stability of cyclophosphamide containing infusions. Pharmazie, 54(3), 224-225.

Stability of cyclophosphamide containing infusions. / Mittner, Andras; Vincze, Z.; Jemnitz, K.

In: Pharmazie, Vol. 54, No. 3, 1999, p. 224-225.

Research output: Contribution to journalArticle

Mittner, A, Vincze, Z & Jemnitz, K 1999, 'Stability of cyclophosphamide containing infusions', Pharmazie, vol. 54, no. 3, pp. 224-225.
Mittner, Andras ; Vincze, Z. ; Jemnitz, K. / Stability of cyclophosphamide containing infusions. In: Pharmazie. 1999 ; Vol. 54, No. 3. pp. 224-225.
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