Spontaneous remission in localized diffuse large b-cell lymphoma

László Tamás, Eszter Sári, Gábor Répássy, Péter Szabó, Eniko Bagdi, László Krenács, Judit Demeter

Research output: Contribution to journalArticle

10 Citations (Scopus)


Diffuse large B-cell lymphoma (DLBCL) is an aggressive neoplastic disease of the lymphatic system, the activated B-cell type of this disease is likely to have a substantially worse prognosis. In this study, we report the favorable outcome of the activated B-cell type of DLBCL, though untreated, 7 years after diagnosis. In 2003, DLBCL localized to the root of tongue was found in the patient complaining of dysphonia and a pharyngeal globus perception but the patient did not agree to get any active hematological treatment. During the following years, the patient did not have any complaints. At the otorhinolaryngological control examination, in 2010, she was complaint-free, had normal laboratory parameters. Moreover a PET-CT scan did not reveal metabolic activity relating to malignancy. The extraordinary disease process can be explained by the spontaneous regression of the activated B-cell type DLBCL. Spontaneous regression of oral lymphoma has been published only exceptionally. To our knowledge, no report of spontaneous regression of activated B-cell type DLBLC has been reported.

Original languageEnglish
Pages (from-to)779-784
Number of pages6
JournalPathology and Oncology Research
Issue number3
Publication statusPublished - Sep 1 2011


  • Activated B-cell type DLBLC
  • Diffuse large B-cell lymphoma
  • Root of tongue
  • Spontaneous remission
  • Untreated lymphoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Oncology
  • Cancer Research

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