Spontaneous N epsilon-methylation and N epsilon-formylation reactions between L-lysine and formaldehyde inhibited by L-ascorbic acid.

L. Trézl, I. Rusznák, E. Tyihák, T. Szarvas, B. Szende

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

For the inhibition of spontaneous N epsilon-methylation and N epsilon-formylation reactions between L-lysine and formaldehyde, L-ascorbic acid proved to be most suitable. The inhibition was not complete unless the molar concentration of ascorbic acid exceeded that of formaldehyde. T.l.c., potentiometric titration, n.m.r. spectroscopy and radiometric analysis were applied in the study of the inhibition process. Formaldehyde was reduced by L-ascorbic acid to ethylene glycol.

Original languageEnglish
Pages (from-to)289-292
Number of pages4
JournalThe Biochemical journal
Volume214
Issue number2
DOIs
Publication statusPublished - Aug 15 1983

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

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