Spontán vetélések a fetopatológiai vizsgálatok anyagában

Translated title of the contribution: Spontaneous miscarriage in the collected material submitted for fetopathological examination

Joó József Gábor, A. Beke, Szigeti Zsanett, Csaba Ákos, Rab Attila, Berkes Enikö, B̈oze Tamás, Papp Zoltán, C. Papp

Research output: Contribution to journalArticle

Abstract

Approximately 65-70% of the conceptions end in miscarriage. As it is considered the most frequently occurring obstetric complication it is of extreme importance to improve our knowledge in this field. In this current publication we have processed the report and the results of fetopathological investigations of 427 products of conception resulting from 378 second-trimester (12-24 gestational weeks) miscarriages at our department in the period of 1995-2006. Malformation could be justified in 11.7% of all of the investigated cases. At the time of miscarriage, the median gestational age in cases with a malformation was found to be 17±2.7 weeks while in cases with no malformation it was 20±2.4 weeks. In one third (33.6%) of the patients there was a positive obstetric and/or gynaecological history. The boy to girl ratio in cases without malformations was quite close (1.03) while in cases with malformations, an expressed boy-dominance of 1.38 could be observed. In fetopathologically proved malformations, the malformation occurred singularly in 35 cases. Most frequently affected system was: the cardiovascular system, to be more precise a single umbilical artery was found in 25% of all the cases affected by malformation. In all our investigated miscarriages intrauterine infection was thought to be the major cause in just over a quarter (25.5%) of the cases. Miscarriage in pregnancies complicated with a malformation is more likely to occur and that also approximately three weeks earlier than in cases without a confirmed malformation. There is practically no difference between the affected and "unaffected" miscarriages regarding the cumulative ratio of positive history. However, an expressed male dominance could be observed in miscarriages associated with malformation, while in other miscarriages the gender distribution of the products of conception has been quite balanced. A single umbilical artery alone predisposes to miscarriage while in association with other malformations it may result in chromosomal aberration.

Original languageHungarian
Pages (from-to)71-77
Number of pages7
JournalMagyar Noorvosok Lapja
Volume71
Issue number2
Publication statusPublished - 2008

Fingerprint

Spontaneous Abortion
Single Umbilical Artery
Obstetrics
History
Second Pregnancy Trimester
Cardiovascular System
Chromosome Aberrations
Gestational Age
Pregnancy
Infection

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

Gábor, J. J., Beke, A., Zsanett, S., Ákos, C., Attila, R., Enikö, B., ... Papp, C. (2008). Spontán vetélések a fetopatológiai vizsgálatok anyagában. Magyar Noorvosok Lapja, 71(2), 71-77.

Spontán vetélések a fetopatológiai vizsgálatok anyagában. / Gábor, Joó József; Beke, A.; Zsanett, Szigeti; Ákos, Csaba; Attila, Rab; Enikö, Berkes; Tamás, B̈oze; Zoltán, Papp; Papp, C.

In: Magyar Noorvosok Lapja, Vol. 71, No. 2, 2008, p. 71-77.

Research output: Contribution to journalArticle

Gábor, JJ, Beke, A, Zsanett, S, Ákos, C, Attila, R, Enikö, B, Tamás, B, Zoltán, P & Papp, C 2008, 'Spontán vetélések a fetopatológiai vizsgálatok anyagában', Magyar Noorvosok Lapja, vol. 71, no. 2, pp. 71-77.
Gábor JJ, Beke A, Zsanett S, Ákos C, Attila R, Enikö B et al. Spontán vetélések a fetopatológiai vizsgálatok anyagában. Magyar Noorvosok Lapja. 2008;71(2):71-77.
Gábor, Joó József ; Beke, A. ; Zsanett, Szigeti ; Ákos, Csaba ; Attila, Rab ; Enikö, Berkes ; Tamás, B̈oze ; Zoltán, Papp ; Papp, C. / Spontán vetélések a fetopatológiai vizsgálatok anyagában. In: Magyar Noorvosok Lapja. 2008 ; Vol. 71, No. 2. pp. 71-77.
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