Spin trapping of superoxide in the presence of β-cyclodextrins

Hakim Karoui, A. Rockenbauer, Sylvie Pietri, Paul Tordo

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

The trapping of superoxide anion with DMPO† and DEPMPO† has been carried out in the presence of a methylated β-cyclodextrin, Me-β-CD†; inclusion of the spin adducts in the cavity of Me-β-CD resulted in a seven-fold increase of their half-life (t1/2 = 96 min for DEPMPO-superoxide spin adduct) and in their protection towards glutathione peroxidase (Gpx) and also ascorbate anion in the case of DEPMPO.

Original languageEnglish
Pages (from-to)3030-3031
Number of pages2
JournalChemical Communications
Volume8
Issue number24
DOIs
Publication statusPublished - 2002

Fingerprint

Cyclodextrins
Superoxides
Negative ions
Glutathione Peroxidase
Anions
Glutathione

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Spin trapping of superoxide in the presence of β-cyclodextrins. / Karoui, Hakim; Rockenbauer, A.; Pietri, Sylvie; Tordo, Paul.

In: Chemical Communications, Vol. 8, No. 24, 2002, p. 3030-3031.

Research output: Contribution to journalArticle

Karoui, Hakim ; Rockenbauer, A. ; Pietri, Sylvie ; Tordo, Paul. / Spin trapping of superoxide in the presence of β-cyclodextrins. In: Chemical Communications. 2002 ; Vol. 8, No. 24. pp. 3030-3031.
@article{5687beed85354320b4f8a4da49b30627,
title = "Spin trapping of superoxide in the presence of β-cyclodextrins",
abstract = "The trapping of superoxide anion with DMPO† and DEPMPO† has been carried out in the presence of a methylated β-cyclodextrin, Me-β-CD†; inclusion of the spin adducts in the cavity of Me-β-CD resulted in a seven-fold increase of their half-life (t1/2 = 96 min for DEPMPO-superoxide spin adduct) and in their protection towards glutathione peroxidase (Gpx) and also ascorbate anion in the case of DEPMPO.",
author = "Hakim Karoui and A. Rockenbauer and Sylvie Pietri and Paul Tordo",
year = "2002",
doi = "10.1039/b209787g",
language = "English",
volume = "8",
pages = "3030--3031",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "24",

}

TY - JOUR

T1 - Spin trapping of superoxide in the presence of β-cyclodextrins

AU - Karoui, Hakim

AU - Rockenbauer, A.

AU - Pietri, Sylvie

AU - Tordo, Paul

PY - 2002

Y1 - 2002

N2 - The trapping of superoxide anion with DMPO† and DEPMPO† has been carried out in the presence of a methylated β-cyclodextrin, Me-β-CD†; inclusion of the spin adducts in the cavity of Me-β-CD resulted in a seven-fold increase of their half-life (t1/2 = 96 min for DEPMPO-superoxide spin adduct) and in their protection towards glutathione peroxidase (Gpx) and also ascorbate anion in the case of DEPMPO.

AB - The trapping of superoxide anion with DMPO† and DEPMPO† has been carried out in the presence of a methylated β-cyclodextrin, Me-β-CD†; inclusion of the spin adducts in the cavity of Me-β-CD resulted in a seven-fold increase of their half-life (t1/2 = 96 min for DEPMPO-superoxide spin adduct) and in their protection towards glutathione peroxidase (Gpx) and also ascorbate anion in the case of DEPMPO.

UR - http://www.scopus.com/inward/record.url?scp=0036923225&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036923225&partnerID=8YFLogxK

U2 - 10.1039/b209787g

DO - 10.1039/b209787g

M3 - Article

AN - SCOPUS:0036923225

VL - 8

SP - 3030

EP - 3031

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 24

ER -