SPECT and TCD studies in cluster headache patients

J. Afra, C. Ertsey, I. Jelencsik, G. Dabasi, G. Panczel

Research output: Contribution to journalArticle

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We investigated regional cerebral blood flow (rCBF) with Tc99m-HMPAO single photon emission computed tomography (SPECT) and blood flow velocity in the middle cerebral artery (MCA) with transcranial Doppler (TCD) ultrasound. Nineteen cluster headache patients participated in the study, 9 of them underwent both examinations, whereas in 6 patients only SPECT and in 4 patients only TCD was performed. Patients were examined during spontaneous and/or provoked attacks and when symptom-free in a cluster period. Six patients showed moderate frontal hyperperfusion, 2 had frontal hypoperfusion whereas no change from headache-free rCBF occurred in 7 patients. Statistical analysis of MCA velocities in 13 patients showed a significant decrease in the mean flow velocity compared with the headache-free values on the symptomatic side. Our findings suggest that the alteration of cerebral circulation during cluster attacks might be of secondary nature.

Original languageEnglish
Pages (from-to)259-264
Number of pages6
JournalFunctional neurology
Issue number6
Publication statusPublished - Dec 1 1995



  • Cluster headache
  • Transcranial Doppler

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

Cite this

Afra, J., Ertsey, C., Jelencsik, I., Dabasi, G., & Panczel, G. (1995). SPECT and TCD studies in cluster headache patients. Functional neurology, 10(6), 259-264.