Specific tritium labelling of lysine‐vasopressin in two different aminoacid residues

Gy Kéri, I. Teplán

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Lysine8‐vasopressin was specifically labelled with tritium in the tyrosine2 and phenylalanine3 residues. The 3, 5‐dibromo‐tyrosine2 and 4‐chloro‐phenylalanine3 derivatives of the hormone were synthesized by solid phase peptide synthesis. The halogen containing peptides were catalytically reduced by tritium gas yielding preparations with high specific radioactivity and full biological activity as compared with reference material.

Original languageEnglish
Pages (from-to)153-162
Number of pages10
JournalJournal of Labelled Compounds and Radiopharmaceuticals
Volume15
Issue number1 S
DOIs
Publication statusPublished - Oct 1978

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ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Radiology Nuclear Medicine and imaging
  • Drug Discovery
  • Spectroscopy
  • Organic Chemistry

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