Specific increase of human entorhinal population synaptic and neuronal activity during retrieval

Susanne Knake, Chun Mao Wang, I. Ulbert, Donald L. Schomer, Eric Halgren

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Population transmembrane currents and neuronal firing in different layers of the human entorhinal cortex (ER) were recorded during semantic and episodic memory processes using a linear array of 24 laminar microelectrodes. Both measures, as well as local broadband spectral power, increased during retrieval of newly-learned characteristics, especially in superficial layers. No differences were observed in the activity evoked by remembering people as compared to places. Semantic retrieval evoked similar activity. In contrast, intentional encoding of declarative memory evoked relatively little activity. A double-dissociation of these responses with simultaneously recorded lateral inferotemporal recordings suggests that entorhinal cortex may be specifically engaged during retrieval, across multiple memory types and materials.

Original languageEnglish
Pages (from-to)618-622
Number of pages5
JournalNeuroImage
Volume37
Issue number2
DOIs
Publication statusPublished - Aug 15 2007

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Entorhinal Cortex
Semantics
Episodic Memory
Microelectrodes
Population
Power (Psychology)

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Neurology

Cite this

Specific increase of human entorhinal population synaptic and neuronal activity during retrieval. / Knake, Susanne; Wang, Chun Mao; Ulbert, I.; Schomer, Donald L.; Halgren, Eric.

In: NeuroImage, Vol. 37, No. 2, 15.08.2007, p. 618-622.

Research output: Contribution to journalArticle

Knake, Susanne ; Wang, Chun Mao ; Ulbert, I. ; Schomer, Donald L. ; Halgren, Eric. / Specific increase of human entorhinal population synaptic and neuronal activity during retrieval. In: NeuroImage. 2007 ; Vol. 37, No. 2. pp. 618-622.
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