Species-specificity of glial vimentin as revealed by immunocytochemical studies with the Vim 3B4 and V9 monoclonal antibodies.

B. Gereben, B. Gerics, P. Gálfi, P. Rudas, F. Hajós, V. Jancsik

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Abstract

Two monoclonal antibodies directed against vimentin, Vim 3B4 and V9 could distinguish between vimentins originating from certain species, when tested on cell lines (Bohn et al, 1992). Our comparative immunohistochemical studies in the rat and chicken brain with the same antibodies suggest the coexistence of two vimentin forms in the glial cells of both species. One of these forms bearing the epitope present in the respective non-glial cell lines is present in astrocytes and Bergmann glia independently of the ontogenic state of the animal. The other epitope appeared also mutually in both species, albeit its expression was more restricted. These patterns suggest that in these two species, the expression of the different vimentin forms might be differently regulated.

Original languageEnglish
Pages (from-to)151-164
Number of pages14
JournalNeurobiology (Budapest, Hungary)
Volume3
Issue number2
Publication statusPublished - 1995

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ASJC Scopus subject areas

  • Neuroscience(all)

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