Some further data on the effects of two organophosphate pesticides on the oxidative metabolism in the liver

B. Matkovics, L. Szabó, J. Iván, I. Gaál

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

1. 1. Sumithion is the most active cholinesterase inhibitor. 2. 2. The cholinesterase inhibiting action of the organophosphates (OPs) is better compensated by vitamin E in normal animals, but by vitamin A in vitamin A-deficient animals. 3. 3. The lipid peroxidation (LP) is enhanced by the antioxidant vitamins in the liver of normal rats; although they decrease it in the liver of vitamin A-deficient animals, in no case do they prevent the LP-enhancing effect of the OPs examined. 4. 4. The OPs examined inhibit protein synthesis in the liver of vitamin A-deficient animals.

Original languageEnglish
Pages (from-to)689-691
Number of pages3
JournalGeneral Pharmacology
Volume14
Issue number6
DOIs
Publication statusPublished - 1983

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Organophosphates
Vitamin A
Pesticides
Liver
Lipid Peroxidation
Fenitrothion
Cholinesterase Inhibitors
Cholinesterases
Vitamin E
Vitamins
Antioxidants
Proteins

ASJC Scopus subject areas

  • Pharmacology

Cite this

Some further data on the effects of two organophosphate pesticides on the oxidative metabolism in the liver. / Matkovics, B.; Szabó, L.; Iván, J.; Gaál, I.

In: General Pharmacology, Vol. 14, No. 6, 1983, p. 689-691.

Research output: Contribution to journalArticle

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