Somatostatin versus secretin in the treatment of actively bleeding gastric erosions

Z. Tulassay, András Bodnár, Ivan Farkas, J. Papp, Ramesh Gupta

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

In a double-blind, prospective, randomized trial, 63 patients with actively bleeding gastric erosions were treated with somatostatin (31 patients) or secretin (32 patients). Both drugs were administered by intravenous infusions for 48 or 72 h. The active bleeding and the effect of the therapy was endoscopically established. Somatostatin had a significantly (p <0.05) better effect on the control of bleeding (29 vs. 23 patients), transfusion requirements (5.8 vs. 7.4 units, p <0.01) and on the need of surgery (1 vs. 6 patients, p <0.01). The mortality and the rebleeding rate did not differ between the two groups. The results show that somatostatin is more effective than secretin in the control of active bleeding form gastric erosions.

Original languageEnglish
Pages (from-to)211-216
Number of pages6
JournalDigestion
Volume51
Issue number4
DOIs
Publication statusPublished - 1992

Fingerprint

Secretin
Somatostatin
Stomach
Hemorrhage
Therapeutics
Intravenous Infusions
Mortality
Pharmaceutical Preparations

Keywords

  • Gastric erosions
  • Gastrointestinal bleeding
  • Secretin
  • Somatostatin

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Somatostatin versus secretin in the treatment of actively bleeding gastric erosions. / Tulassay, Z.; Bodnár, András; Farkas, Ivan; Papp, J.; Gupta, Ramesh.

In: Digestion, Vol. 51, No. 4, 1992, p. 211-216.

Research output: Contribution to journalArticle

Tulassay, Z. ; Bodnár, András ; Farkas, Ivan ; Papp, J. ; Gupta, Ramesh. / Somatostatin versus secretin in the treatment of actively bleeding gastric erosions. In: Digestion. 1992 ; Vol. 51, No. 4. pp. 211-216.
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