Somatostatin-immunoreactive nerve fibers in close association with capillaries in the small intestine

E. Fehér, T. Görcs, G. Burnstock

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Electron microscopic immunocytochemistry was used to identify somatostatin-immunoreactive nerve profiles around the capillary system of the small intestine in the rat and cat. The highest density of somatostatin-immunoreactive nerve profiles was seen in the mucosa, and 25-30% of all immunoreactive profiles were found immediately adjacent to the endothelial cells of capillary blood vessels. About half of the capillary endothelial cells were fenestrated. The majority of the immunoreactive nerve profiles were varicosities, containing synaptic vesicles. These observations suggest that somatostatin might be released from varicose nerve fibers and may contribute to the elevated levels of the peptide measured in portal blood as compared to peripheral blood.

Original languageEnglish
Pages (from-to)945-949
Number of pages5
JournalPeptides
Volume10
Issue number5
DOIs
Publication statusPublished - 1989

Fingerprint

Somatostatin
Nerve Fibers
Small Intestine
Endothelial cells
Fibers
Blood
Endothelial Cells
Synaptic Vesicles
Blood vessels
Blood Vessels
Rats
Mucous Membrane
Cats
Immunohistochemistry
Electrons
Peptides

Keywords

  • Capillary wall
  • Immunocytochemistry
  • Somatostatin

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology
  • Physiology
  • Cellular and Molecular Neuroscience

Cite this

Somatostatin-immunoreactive nerve fibers in close association with capillaries in the small intestine. / Fehér, E.; Görcs, T.; Burnstock, G.

In: Peptides, Vol. 10, No. 5, 1989, p. 945-949.

Research output: Contribution to journalArticle

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