Somatostatin connections between the hypothalamus and the limbic system of the rat brain

M. Palkóvits, L. Tapia-Arancibia, C. Kordon, J. Epelbaum

Research output: Contribution to journalArticle

63 Citations (Scopus)

Abstract

Somatostatin (SRIF) content of several brain structures was evaluated by radioimmunoassay in rats bearing various types of hypothalamic transections, as well as lesions of the amygdala. Analysis of the regional changes in SRIF concentrations after surgery suggest the following conclusions: (1) hypothalamic somatostatinergic neurons project to the limbic system, with the exception of the amygdaloid nuclei; (2) the olfactory tubercle, the lateral septal nucleus, the habenula and probably the hippocampus receive somatostatin projections from periventricular SRIF-containing cells; (3) somatostatin-containing fibers take a lateral course after leaving periventricular cells and join the medial forebrain bundle; (4) somatostatin innervation of the amygdala seems to be intrinsic.

Original languageEnglish
Pages (from-to)223-228
Number of pages6
JournalBrain Research
Volume250
Issue number2
DOIs
Publication statusPublished - Nov 4 1982

Fingerprint

Limbic System
Somatostatin
Hypothalamus
Amygdala
Brain
Medial Forebrain Bundle
Habenula
Septal Nuclei
Radioimmunoassay
Hippocampus
Neurons

Keywords

  • amygdala
  • habenula
  • hippocampus
  • olfactory tubercle
  • radioimmunoassay
  • septum
  • somatostatin
  • surgical transections

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Somatostatin connections between the hypothalamus and the limbic system of the rat brain. / Palkóvits, M.; Tapia-Arancibia, L.; Kordon, C.; Epelbaum, J.

In: Brain Research, Vol. 250, No. 2, 04.11.1982, p. 223-228.

Research output: Contribution to journalArticle

Palkóvits, M. ; Tapia-Arancibia, L. ; Kordon, C. ; Epelbaum, J. / Somatostatin connections between the hypothalamus and the limbic system of the rat brain. In: Brain Research. 1982 ; Vol. 250, No. 2. pp. 223-228.
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