A szomatosztatin és az emésztorendszer. Klinikai tapasztalatok

Translated title of the contribution: Somatostatin and gastrointestinal tract. Clinical experiences

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The effect of somatostatin on the gastrointestinal tract is complex; it inhibits the release of gastrointestinal hormones, the exocrine function of the stomach, pancreas and bile, decreases motility and influences absorption as well. Based on these diverse effects there was an increased expectation towards the success of somatostatin therapy in various gastrointestinal disorders. The preconditions for somatostatin treatment was created by the development of long acting somatostatin analogues (octreotide, lanreotide). During the last twenty-five years large trials clarified the role of somatostatin analogues in the treatment of various gastrointestinal diseases. This study summarizes shortly these results. Somatostatin analogue treatment could be effective in various pathological conditions of the gastrointestinal tract, however, this therapeutic modality became a part of the clinical routine only in neuroendocrine tumours and adjuvant treatment of oesophageal variceal bleeding and pancreatic fistulas.

Original languageHungarian
Pages (from-to)1535-1540
Number of pages6
JournalOrvosi hetilap
Volume154
Issue number39
DOIs
Publication statusPublished - Sep 1 2013

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ASJC Scopus subject areas

  • Medicine(all)

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