Somato-dendritic synapses in the nucleus reticularis thalami of the rat

B. Csillik, A. Pálfi, K. Gulya, A. Mihály, Elizabeth Knyihá-Csillik

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

In the reticular nucleus of the rat thalamus, about 30% of the synapses are brought about by the perikarya of parvalbumin-immunopositive neurons, which establish somato-dendritic synapses with large dendrites of nerve cells of specific thalamic nuclei. Although the parvalbumin-immunopositive presynaptic structures bear resemblance to goblet-like or calyciform axonal endings, electron microscopic immunocytochemistry and in situ hybridization revealed that these structures are parts of the perikaryal cytoplasm studded with synaptic vesicles. In about 15% of the somato-dendritic synapses, axons are seen to be in synaptic contact with the parvalbumin-immunoreactive perikaryon. Double immunohistochemical staining revealed that the parvalbumin immunoreactive presynaptic perikarya and dendrites contained GABA. It is assumed that the peculiar somato-dendritic synaptic complexes subserve the goal of filtration of impulses arriving at the reticular nucleus from various thalamic nuclei, thus processing them for further sampling.

Original languageEnglish
Pages (from-to)33-41
Number of pages9
JournalActa biologica Hungarica
Volume53
Issue number1-2
DOIs
Publication statusPublished - May 2 2002

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Keywords

  • Dendritic synapses
  • GABA
  • Parvalbumin
  • Reticular nucleus
  • Somato
  • Thalamus

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Environmental Science(all)
  • Neurology

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