Somatic cell nuclear transfer

I. Wilmut, N. Beaujean, P. A. De Sousa, A. Dinnyés, T. J. King, L. A. Paterson, D. N. Wells, L. E. Young

Research output: Contribution to journalArticle

375 Citations (Scopus)

Abstract

Cloning by nuclear transfer from adult somatic cells is a remarkable demonstration of developmental plasticity. When a nucleus is placed in oocyte cytoplasm, the changes in chromatin structure that govern differentiation can be reversed, and the nucleus can be made to control development to term.

Original languageEnglish
Pages (from-to)583-586
Number of pages4
JournalNature
Volume419
Issue number6907
Publication statusPublished - Oct 10 2002

Fingerprint

Chromatin
Oocytes
Organism Cloning
Cytoplasm

ASJC Scopus subject areas

  • General

Cite this

Wilmut, I., Beaujean, N., De Sousa, P. A., Dinnyés, A., King, T. J., Paterson, L. A., ... Young, L. E. (2002). Somatic cell nuclear transfer. Nature, 419(6907), 583-586.

Somatic cell nuclear transfer. / Wilmut, I.; Beaujean, N.; De Sousa, P. A.; Dinnyés, A.; King, T. J.; Paterson, L. A.; Wells, D. N.; Young, L. E.

In: Nature, Vol. 419, No. 6907, 10.10.2002, p. 583-586.

Research output: Contribution to journalArticle

Wilmut, I, Beaujean, N, De Sousa, PA, Dinnyés, A, King, TJ, Paterson, LA, Wells, DN & Young, LE 2002, 'Somatic cell nuclear transfer', Nature, vol. 419, no. 6907, pp. 583-586.
Wilmut I, Beaujean N, De Sousa PA, Dinnyés A, King TJ, Paterson LA et al. Somatic cell nuclear transfer. Nature. 2002 Oct 10;419(6907):583-586.
Wilmut, I. ; Beaujean, N. ; De Sousa, P. A. ; Dinnyés, A. ; King, T. J. ; Paterson, L. A. ; Wells, D. N. ; Young, L. E. / Somatic cell nuclear transfer. In: Nature. 2002 ; Vol. 419, No. 6907. pp. 583-586.
@article{9d8faedc2c28419aabff0e7a2dfe9486,
title = "Somatic cell nuclear transfer",
abstract = "Cloning by nuclear transfer from adult somatic cells is a remarkable demonstration of developmental plasticity. When a nucleus is placed in oocyte cytoplasm, the changes in chromatin structure that govern differentiation can be reversed, and the nucleus can be made to control development to term.",
author = "I. Wilmut and N. Beaujean and {De Sousa}, {P. A.} and A. Dinny{\'e}s and King, {T. J.} and Paterson, {L. A.} and Wells, {D. N.} and Young, {L. E.}",
year = "2002",
month = "10",
day = "10",
language = "English",
volume = "419",
pages = "583--586",
journal = "Nature",
issn = "0028-0836",
publisher = "Nature Publishing Group",
number = "6907",

}

TY - JOUR

T1 - Somatic cell nuclear transfer

AU - Wilmut, I.

AU - Beaujean, N.

AU - De Sousa, P. A.

AU - Dinnyés, A.

AU - King, T. J.

AU - Paterson, L. A.

AU - Wells, D. N.

AU - Young, L. E.

PY - 2002/10/10

Y1 - 2002/10/10

N2 - Cloning by nuclear transfer from adult somatic cells is a remarkable demonstration of developmental plasticity. When a nucleus is placed in oocyte cytoplasm, the changes in chromatin structure that govern differentiation can be reversed, and the nucleus can be made to control development to term.

AB - Cloning by nuclear transfer from adult somatic cells is a remarkable demonstration of developmental plasticity. When a nucleus is placed in oocyte cytoplasm, the changes in chromatin structure that govern differentiation can be reversed, and the nucleus can be made to control development to term.

UR - http://www.scopus.com/inward/record.url?scp=0037057695&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037057695&partnerID=8YFLogxK

M3 - Article

C2 - 12374931

AN - SCOPUS:0037057695

VL - 419

SP - 583

EP - 586

JO - Nature

JF - Nature

SN - 0028-0836

IS - 6907

ER -