Solvent-free, mild, facile, and rapid one-pot three-component synthesis of some novel imidazo[2,1-b]naphtho[1,2-e][1,3] thiazin-10-ones using p-TSA

Mohammad M. Ghanbari, Marzieh Jamali, G. Batta

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Novel [2,1-b]naphtho[1,2-e][1,3]thiazin-10-ones were synthesized in 63-89% yield via a three-component reaction of an aromatic aldehyde, β-naphthol, and thiohydantoin in the presence of 10 mol% p-toluene sulfonic acid under solvent-free conditions. This is the first protocol to be reported for the synthesis of the title compounds. The significant features of the present protocol are simplicity, high yields, eco-friendliness, and convenient purification that does not require chromatography.

Original languageEnglish
Pages (from-to)394-398
Number of pages5
JournalJournal of Sulfur Chemistry
Volume35
Issue number4
DOIs
Publication statusPublished - Jul 4 2014

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Thiohydantoins
Naphthols
Chromatography
Aldehydes
Purification
4-toluenesulfonic acid

Keywords

  • aldehyde
  • â-naphthol
  • one-pot reaction
  • solvent-free
  • thiohydantoins

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Solvent-free, mild, facile, and rapid one-pot three-component synthesis of some novel imidazo[2,1-b]naphtho[1,2-e][1,3] thiazin-10-ones using p-TSA. / Ghanbari, Mohammad M.; Jamali, Marzieh; Batta, G.

In: Journal of Sulfur Chemistry, Vol. 35, No. 4, 04.07.2014, p. 394-398.

Research output: Contribution to journalArticle

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