Solvatochromic isocyanonaphthalene dyes as ligands for silver(I) complexes, their applicability in silver(I) detection and background reduction in biolabelling

Miklós Nagy, Dávid Rácz, Zsolt László Nagy, Péter Pál Fehér, József Kalmár, I. Fábián, Alexandra Kiss, M. Zsuga, S. Kéki

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The complexation behavior of reactive and nonreactive N-substituted 1-amino-5-isocyanonaphthalene (ICAN) derivatives was studied in the presence of Ag(I) ions by UV–vis, steady-state and time resolved fluorescence measurements. The effect of ligand, solvent and counterion is covered. The equilibrium constants were found to be KAgL ∼ 106 M−1 in dioxane and water. Complex formation results a significant, solvent dependent (30–59 nm) batochromic shift of the emission maximum. This shift is accompanied by a switch-off effect in the case of the unreactive ligands, while in the case of the acrylated derivative (ACAIN) significant intensity enhancement was detected. Based on spectroscopic results only 1:1 AgL complex could be detected in solution at low concentrations cAgL <10−4 M, while at higher concentrations pure 1:2 AgL2 formed which was characterized by ESI–MS, IR and NMR methods The structure and optical behavior of the complexes are discussed based on high-level quantum chemical calculations. It is shown that the complexation of ACAIN can be used for the selective detection and quantification of silver(I) ions from aqueous media. In addition, the fluorescene switch-off in the case of MICAN yields a significant contrast enhancement in biolabeling applications as is shown on fixated HaCat cells.s

Original languageEnglish
Pages (from-to)2555-2567
Number of pages13
JournalSensors and Actuators, B: Chemical
Volume255
DOIs
Publication statusPublished - Feb 1 2018

Fingerprint

Complexation
Silver
Coloring Agents
switches
Dyes
dyes
Ligands
silver
Switches
Ions
Derivatives
ligands
augmentation
shift
Equilibrium constants
low concentrations
ions
Fluorescence
Nuclear magnetic resonance
fluorescence

Keywords

  • Complex
  • Fluorescence
  • Isonitrile
  • Silver(I)
  • Solvatochromic effect

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Instrumentation
  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Electrical and Electronic Engineering
  • Materials Chemistry

Cite this

Solvatochromic isocyanonaphthalene dyes as ligands for silver(I) complexes, their applicability in silver(I) detection and background reduction in biolabelling. / Nagy, Miklós; Rácz, Dávid; Nagy, Zsolt László; Fehér, Péter Pál; Kalmár, József; Fábián, I.; Kiss, Alexandra; Zsuga, M.; Kéki, S.

In: Sensors and Actuators, B: Chemical, Vol. 255, 01.02.2018, p. 2555-2567.

Research output: Contribution to journalArticle

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AU - Nagy, Zsolt László

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AU - Kalmár, József

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