Soluble L-selectin levels in serum and cerebrospinal fluid in patients with multiple sclerosis and systemic lupus erythematosus

K. Baraczka, T. Pozsonyi, K. Nékám, M. Virányi, M. Seszták, M. Szongoth, L. Jakab

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Soluble L-selectin (sL-selectin) concentrations were measured in paired samples of serum and cerebrospinal fluid by an ELISA method. Patients with several forms of multiple sclerosis (MS) and systemic lupus erythematosus with central nervous system involvement (SLE-CNS) were investigated. Elevated CSF sL-selectin concentrations were found in patients with SLE-CNS (7.62 ± 3.31 ng/ml) and with relapsing - remitting form of MS (6.99 ± 4.72 ng/ml) compared to the control group (4.00 ± 0.95 ng/ml). The data presented suggest some similarities between inflammatory/immunological events in the central nervous system in patients with SLE-CNS and relapsing-remitting form of MS. Immunological heterogeneity in MS is suspected.

Original languageEnglish
Pages (from-to)114-117
Number of pages4
JournalActa Neurologica Scandinavica
Volume102
Issue number2
DOIs
Publication statusPublished - 2000

Keywords

  • Cerebrospinal fluid
  • Multiple sclerosis
  • Soluble L-selectin
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Soluble L-selectin levels in serum and cerebrospinal fluid in patients with multiple sclerosis and systemic lupus erythematosus'. Together they form a unique fingerprint.

  • Cite this