Socioeconomic factors are associated with folate and vitamin B12 intakes and related biomarkers concentrations in European adolescents

The Healthy Lifestyle in Europe by Nutrition in Adolescence study

Iris Iglesia, Theodora Mouratidou, Marcela González-Gross, Romana Novakovic, Christina Breidenassel, David Jiménez-Pavón, Inge Huybrechts, Stefaan De Henauw, Anouk Geelen, Frédéric Gottrand, Anthony Kafatos, Lorenza Mistura, Fátima Pérez De Heredia, Kurt Widhalm, Yanis Manios, Denes Molnar, Peter Stehle, Mirjana Gurinovic, Adrienne E J M Cavelaars, Pieter Van t Veer & 1 others Luis A. Moreno

Research output: Contribution to journalArticle

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Abstract

Because socioeconomic factors (SEFs) may influence dietary quality and vitamin intakes, this study aimed to examine associations between socioeconomic factors and folate and vitamin B12 intakes as well as their related biomarkers in the Healthy Lifestyle in Europe by Nutrition in Adolescence study. Vitamin intakes were obtained from two 24-hour recalls in 2253 participants (47% males). Vitamin B biomarkers were assessed in a subsample of 977 participants (46% males). Socioeconomic factors were assessed by questionnaire, and 1-way analysis of covariance and linear regression analysis were applied. For males and females, mean intakes of folate were 211.19 and 177.18μg/d, and for vitamin B12, 5.98 and 4.54μg/d, respectively. Levels of plasma folate, red blood cell folate, serum B12, and holotranscobalamin were 18.74, 807.19, 330.64, and 63.04nmol/L in males, respectively, and 19.13, 770.16, 377.9, and 65.63nmol/L in females, respectively. Lower folate intakes were associated with several SEFs, including maternal and paternal education in both sexes. Regarding folate biomarkers, lower plasma folate intakes were associated with single/shared care in males and with lower paternal occupation in females. Lower vitamin B12 intakes were associated with almost all the studied SEFs, except paternal occupation in both sexes. In females, when considering vitamin B12 biomarkers, lower plasma vitamin B12 was associated with lower maternal education and occupation, and lower holotranscobalamin was associated with lower maternal education and lower paternal occupation. In conclusion, from the set of socioeconomic determinants studied in a sample of European adolescents, maternal education and paternal occupation were more consistently associated with folate and vitamin B12 intakes and biomarkers concentrations.

Original languageEnglish
Pages (from-to)199-209
Number of pages11
JournalNutrition Research
Volume34
Issue number3
DOIs
Publication statusPublished - 2014

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Vitamin B 12
Folic Acid
Biomarkers
Occupations
Mothers
Education
Vitamins
Vitamin B Complex
Healthy Lifestyle
Linear Models
Erythrocytes
Regression Analysis
Serum

Keywords

  • Adolescent
  • Cross-sectional
  • Europe
  • Folic acid
  • Socioeconomic factors

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics

Cite this

Socioeconomic factors are associated with folate and vitamin B12 intakes and related biomarkers concentrations in European adolescents : The Healthy Lifestyle in Europe by Nutrition in Adolescence study. / Iglesia, Iris; Mouratidou, Theodora; González-Gross, Marcela; Novakovic, Romana; Breidenassel, Christina; Jiménez-Pavón, David; Huybrechts, Inge; De Henauw, Stefaan; Geelen, Anouk; Gottrand, Frédéric; Kafatos, Anthony; Mistura, Lorenza; De Heredia, Fátima Pérez; Widhalm, Kurt; Manios, Yanis; Molnar, Denes; Stehle, Peter; Gurinovic, Mirjana; Cavelaars, Adrienne E J M; Veer, Pieter Van t; Moreno, Luis A.

In: Nutrition Research, Vol. 34, No. 3, 2014, p. 199-209.

Research output: Contribution to journalArticle

Iglesia, I, Mouratidou, T, González-Gross, M, Novakovic, R, Breidenassel, C, Jiménez-Pavón, D, Huybrechts, I, De Henauw, S, Geelen, A, Gottrand, F, Kafatos, A, Mistura, L, De Heredia, FP, Widhalm, K, Manios, Y, Molnar, D, Stehle, P, Gurinovic, M, Cavelaars, AEJM, Veer, PVT & Moreno, LA 2014, 'Socioeconomic factors are associated with folate and vitamin B12 intakes and related biomarkers concentrations in European adolescents: The Healthy Lifestyle in Europe by Nutrition in Adolescence study', Nutrition Research, vol. 34, no. 3, pp. 199-209. https://doi.org/10.1016/j.nutres.2014.01.006
Iglesia, Iris ; Mouratidou, Theodora ; González-Gross, Marcela ; Novakovic, Romana ; Breidenassel, Christina ; Jiménez-Pavón, David ; Huybrechts, Inge ; De Henauw, Stefaan ; Geelen, Anouk ; Gottrand, Frédéric ; Kafatos, Anthony ; Mistura, Lorenza ; De Heredia, Fátima Pérez ; Widhalm, Kurt ; Manios, Yanis ; Molnar, Denes ; Stehle, Peter ; Gurinovic, Mirjana ; Cavelaars, Adrienne E J M ; Veer, Pieter Van t ; Moreno, Luis A. / Socioeconomic factors are associated with folate and vitamin B12 intakes and related biomarkers concentrations in European adolescents : The Healthy Lifestyle in Europe by Nutrition in Adolescence study. In: Nutrition Research. 2014 ; Vol. 34, No. 3. pp. 199-209.
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T2 - The Healthy Lifestyle in Europe by Nutrition in Adolescence study

AU - Iglesia, Iris

AU - Mouratidou, Theodora

AU - González-Gross, Marcela

AU - Novakovic, Romana

AU - Breidenassel, Christina

AU - Jiménez-Pavón, David

AU - Huybrechts, Inge

AU - De Henauw, Stefaan

AU - Geelen, Anouk

AU - Gottrand, Frédéric

AU - Kafatos, Anthony

AU - Mistura, Lorenza

AU - De Heredia, Fátima Pérez

AU - Widhalm, Kurt

AU - Manios, Yanis

AU - Molnar, Denes

AU - Stehle, Peter

AU - Gurinovic, Mirjana

AU - Cavelaars, Adrienne E J M

AU - Veer, Pieter Van t

AU - Moreno, Luis A.

PY - 2014

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N2 - Because socioeconomic factors (SEFs) may influence dietary quality and vitamin intakes, this study aimed to examine associations between socioeconomic factors and folate and vitamin B12 intakes as well as their related biomarkers in the Healthy Lifestyle in Europe by Nutrition in Adolescence study. Vitamin intakes were obtained from two 24-hour recalls in 2253 participants (47% males). Vitamin B biomarkers were assessed in a subsample of 977 participants (46% males). Socioeconomic factors were assessed by questionnaire, and 1-way analysis of covariance and linear regression analysis were applied. For males and females, mean intakes of folate were 211.19 and 177.18μg/d, and for vitamin B12, 5.98 and 4.54μg/d, respectively. Levels of plasma folate, red blood cell folate, serum B12, and holotranscobalamin were 18.74, 807.19, 330.64, and 63.04nmol/L in males, respectively, and 19.13, 770.16, 377.9, and 65.63nmol/L in females, respectively. Lower folate intakes were associated with several SEFs, including maternal and paternal education in both sexes. Regarding folate biomarkers, lower plasma folate intakes were associated with single/shared care in males and with lower paternal occupation in females. Lower vitamin B12 intakes were associated with almost all the studied SEFs, except paternal occupation in both sexes. In females, when considering vitamin B12 biomarkers, lower plasma vitamin B12 was associated with lower maternal education and occupation, and lower holotranscobalamin was associated with lower maternal education and lower paternal occupation. In conclusion, from the set of socioeconomic determinants studied in a sample of European adolescents, maternal education and paternal occupation were more consistently associated with folate and vitamin B12 intakes and biomarkers concentrations.

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