Social support decreases depressogenic effect of low-dose interferon alpha treatment in melanoma patients

Péter Kovács, Gitta Pánczél, Tímea Balatoni, Gabriella Liszkay, X. Gonda, G. Bagdy, G. Juhász

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Objective: The most frequent serious psychological side effect of immune therapies is depression. In the present study, we tested whether social support, as a positive environmental effect, is able to moderate depression or anxiety symptoms in melanoma patients during adjuvant low-dose interferon treatment. Methods: Hundred and twenty-seven melanoma patients with negative psychiatric history were included in our longitudinal study and followed up for one year. Depression and anxiety symptoms were measured six times during treatment: at baseline, at 1st, 3rd, 6th, 9th and 12th month of the therapy. In addition, social support was investigated with the Social Dimension Scale. Results: Depressive symptoms significantly increased during the 12-month follow-up period (p.

Original languageEnglish
Pages (from-to)579-584
Number of pages6
JournalJournal of Psychosomatic Research
Volume78
Issue number6
DOIs
Publication statusPublished - Jun 1 2015

Fingerprint

Interferon-alpha
Social Support
Melanoma
Depression
Anxiety
Therapeutics
Interferons
Psychiatry
Longitudinal Studies
Psychology

Keywords

  • Anxiety
  • Depression
  • Interferon
  • Malignant melanoma
  • Proinflammatory cytokine pathway
  • Social support

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Psychology
  • Medicine(all)

Cite this

Social support decreases depressogenic effect of low-dose interferon alpha treatment in melanoma patients. / Kovács, Péter; Pánczél, Gitta; Balatoni, Tímea; Liszkay, Gabriella; Gonda, X.; Bagdy, G.; Juhász, G.

In: Journal of Psychosomatic Research, Vol. 78, No. 6, 01.06.2015, p. 579-584.

Research output: Contribution to journalArticle

Kovács, Péter ; Pánczél, Gitta ; Balatoni, Tímea ; Liszkay, Gabriella ; Gonda, X. ; Bagdy, G. ; Juhász, G. / Social support decreases depressogenic effect of low-dose interferon alpha treatment in melanoma patients. In: Journal of Psychosomatic Research. 2015 ; Vol. 78, No. 6. pp. 579-584.
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