Smoking following renal transplantation in Hungary and its possible deleterious effect on renal graft function

P. Gombos, R. Langer, R. Korbely, M. Varga, A. Kaposi, E. Dinya, V. Müller

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Smoking is a known risk factor for kidney damage and also influences graft function following renal transplantation. Because smoking habits following kidney transplantation are not systematically evaluated, we analyzed them in a single center in Hungary. The survey was conducted among 402 randomly selected kidney graft recipients. We assessed smoking-related questions as well as clinical kidney disease and transplantation data. Posttransplantation renal function was analyzed based on serum creatinine values at 1 month and at 3 years after transplantation. In our study 25% (n = 102) of patients continued to smoke after transplantation. Smokers who received grafts displayed a significantly younger age compared with nonsmokers (40.1 ± 13.4 vs 47.1 ± 12.7 years; P <.001) independent of underlying kidney disease. Posttransplantation kidney function in smokers did not differ at 1 month after engraftment, but was significantly impaired at 3 years as assessed based on serum creatinine levels: 138.9 ± 42.4 versus 128.4 ± 48.5 μmol/L (P <.05). Decrease of renal function correlated with smoking intensity defined in pack-years (r2 = 0.102; P <.05). Smoking is common following kidney transplantation in Hungary and might represent a risk factor for kidney damage following renal transplantation. Therefore, effective tobacco-dependence treatment is necessary in this patient population.

Original languageEnglish
Pages (from-to)2357-2359
Number of pages3
JournalTransplantation Proceedings
Volume42
Issue number6
DOIs
Publication statusPublished - Jul 2010

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Hungary
Kidney Transplantation
Smoking
Transplants
Kidney
Kidney Diseases
Creatinine
Transplantation
Tobacco Use Disorder
Serum
Smoke
Habits
Population

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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Smoking following renal transplantation in Hungary and its possible deleterious effect on renal graft function. / Gombos, P.; Langer, R.; Korbely, R.; Varga, M.; Kaposi, A.; Dinya, E.; Müller, V.

In: Transplantation Proceedings, Vol. 42, No. 6, 07.2010, p. 2357-2359.

Research output: Contribution to journalArticle

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