Size distribution, pulmonary deposition and chemical composition of Hungarian biosoluble glass fibers

Réka Szöke, Bálint Alföldy, I. Balásházy, Werner Hofmann, Ibolya Sziklai-László

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Compared to spherical particles, inhaled fibers may cause enhanced adverse health effects because of their specific shape, thus acting as so-called physical carcinogens. The chemical composition of fibers plays a determining role on the durability and hence may play a potential role in related health effects due to their toxic components. The physical properties, that is, length, diameter, and size distribution, and the chemical composition of fiberglass materials sampled at a Hungarian glass wool factory were investigated. The morphology of the particles was studied by optical microscopy and scanning electron microscopy (SEM), while for the chemical analysis instrumental neutron activation analysis (INAA) and SEM combined with energy-dispersive x-ray analysis (EDX) were used. Deposition fractions of the fibers in different regions of the lung and in the whole human respiratory system were computed by a stochastic lung deposition model for different flow rates and equivalent diameters, using experimentally determined size distributions.

Original languageEnglish
Pages (from-to)325-332
Number of pages8
JournalInhalation Toxicology
Volume19
Issue number4
DOIs
Publication statusPublished - Jan 2007

Fingerprint

Electron Scanning Microscopy
Neutron Activation Analysis
Lung
Fibers
Wool
Poisons
Health
Chemical analysis
Respiratory System
Carcinogens
Respiratory system
Glass
Microscopy
Scanning electron microscopy
Neutron activation analysis
X-Rays
Optical microscopy
Industrial plants
Durability
Physical properties

ASJC Scopus subject areas

  • Toxicology
  • Health, Toxicology and Mutagenesis

Cite this

Size distribution, pulmonary deposition and chemical composition of Hungarian biosoluble glass fibers. / Szöke, Réka; Alföldy, Bálint; Balásházy, I.; Hofmann, Werner; Sziklai-László, Ibolya.

In: Inhalation Toxicology, Vol. 19, No. 4, 01.2007, p. 325-332.

Research output: Contribution to journalArticle

Szöke, Réka ; Alföldy, Bálint ; Balásházy, I. ; Hofmann, Werner ; Sziklai-László, Ibolya. / Size distribution, pulmonary deposition and chemical composition of Hungarian biosoluble glass fibers. In: Inhalation Toxicology. 2007 ; Vol. 19, No. 4. pp. 325-332.
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