Sinus floor elevation using autogenous bone or bone substitute combined with platelet-rich plasma

Karl Andreas Schlegel, Robert Zimmermann, Michael Thorwarth, Friedrich Wilhelm Neukam, Boworn Klongnoi, Emeka Nkenke, E. Felszeghy

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Objective: Sinus augmentation is a common approach for patients with severe alveolar ridge atrophy. However, autogenous bone sometimes results in donor site complications. Bone substitutes with platelet-rich plasma (PRP) promote early bone formation with autogenous bone. Use of PRP on autogenous bone and a bovine bone substitute were investigated in this split-mouth animal study. Study design: Premolars were extracted from minipigs. Each animal received sinus augmentation using a lateral approach with simultaneous insertion of 3 implants in each site. Groups were randomized using autogenous bone alone and combined with PRP or a bovine hydroxyapatite alone in combination with PRP. Results: Microradiographic findings in the autogenous group did not show significantly different rates by using autogenous bone alone or combined with PRP. Using the bovine hydroxyapatite as augmentation material only at 8 weeks, a nonsignificant effect in the PRP group could be seen. At all other observation periods, no significant influence was observed. Conclusion: No significant influence of PRP was found.

Original languageEnglish
JournalOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology
Volume104
Issue number3
DOIs
Publication statusPublished - Sep 2007

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Bone Substitutes
Platelet-Rich Plasma
Bone and Bones
Durapatite
Miniature Swine
Alveolar Process
Bicuspid
Osteogenesis
Atrophy
Mouth
Observation
Tissue Donors

ASJC Scopus subject areas

  • Dentistry(all)
  • Pathology and Forensic Medicine
  • Radiology Nuclear Medicine and imaging
  • Surgery

Cite this

Sinus floor elevation using autogenous bone or bone substitute combined with platelet-rich plasma. / Schlegel, Karl Andreas; Zimmermann, Robert; Thorwarth, Michael; Neukam, Friedrich Wilhelm; Klongnoi, Boworn; Nkenke, Emeka; Felszeghy, E.

In: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology, Vol. 104, No. 3, 09.2007.

Research output: Contribution to journalArticle

Schlegel, Karl Andreas ; Zimmermann, Robert ; Thorwarth, Michael ; Neukam, Friedrich Wilhelm ; Klongnoi, Boworn ; Nkenke, Emeka ; Felszeghy, E. / Sinus floor elevation using autogenous bone or bone substitute combined with platelet-rich plasma. In: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology. 2007 ; Vol. 104, No. 3.
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AU - Nkenke, Emeka

AU - Felszeghy, E.

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