Kombinált hasnyálmirigy-veseátültetés--veseelégtelenséggel szövodött 1. típusú diabetes mellitus kezelésének alternatív módja.

Translated title of the contribution: Simultaneous pancreas-kidney transplantation--an alternative option for the treatment of type 1 diabetes mellitus with renal failure

Károly Kalmár Nagy, János Baumann, Péter Szakály, Iván Gyori Molnár, I. Wittmann, Peter Lodge, Péter Horváth Ors

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

INTRODUCTION: Simultaneous pancreas kidney (SPK) transplantation is the only routinely used therapeutic option which can provide insulin independence, euglycemia and good renal replacement. AIMS: Analysis of the five years' experience of the first Hungarian SPK transplants. MATERIAL: From 29 October 1998. through 31 December 2003. 32 SPK transplants were performed from 53 type 1 diabetes mellitus patients with ESRD on the waiting list. Enteric drainage was performed in all transplanted patients in 20 combined with systemic venous drainage, whereas in 12 patients portal venous drainage was used. In 18 patients only maintenance immunosuppression was administered without ATG induction therapy. Anti IL-2R antibody, daclizumab was given as induction therapy in 14 patients. RESULTS: 24 patients out of 32 transplanted are insulin independent with excellent renal function. 2 patients were lost in the perioperative period due to septic complication. 2 patients died 5 months after transplantation. 1 patient became insulin dependent in 7 month following the SPK transplant, while preserving a marginal renal function. One patient became insulin dependent 2 years after the SPK transplant and was returned to chronic hemodialysis treatment one more year later. 2 patients are insulin independent but lost his renal graft due to therapy resistant rejection. CONCLUSION: SPK transplant is a routinely used therapeutic option with good survival rate and good quality of life for type I diabetes mellitus patients with ESRD.

Original languageHungarian
Pages (from-to)1259-1264
Number of pages6
JournalOrvosi Hetilap
Volume145
Issue number24
Publication statusPublished - Jun 13 2004

Fingerprint

Pancreas Transplantation
Type 1 Diabetes Mellitus
Kidney Transplantation
Renal Insufficiency
Kidney
Pancreas
Transplants
Insulin
Therapeutics
Drainage
Chronic Kidney Failure
Perioperative Period
Waiting Lists
Immunosuppression
Renal Dialysis
Survival Rate
Transplantation
Maintenance
Quality of Life

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Kalmár Nagy, K., Baumann, J., Szakály, P., Gyori Molnár, I., Wittmann, I., Lodge, P., & Horváth Ors, P. (2004). Kombinált hasnyálmirigy-veseátültetés--veseelégtelenséggel szövodött 1. típusú diabetes mellitus kezelésének alternatív módja. Orvosi Hetilap, 145(24), 1259-1264.

Kombinált hasnyálmirigy-veseátültetés--veseelégtelenséggel szövodött 1. típusú diabetes mellitus kezelésének alternatív módja. / Kalmár Nagy, Károly; Baumann, János; Szakály, Péter; Gyori Molnár, Iván; Wittmann, I.; Lodge, Peter; Horváth Ors, Péter.

In: Orvosi Hetilap, Vol. 145, No. 24, 13.06.2004, p. 1259-1264.

Research output: Contribution to journalArticle

Kalmár Nagy, K, Baumann, J, Szakály, P, Gyori Molnár, I, Wittmann, I, Lodge, P & Horváth Ors, P 2004, 'Kombinált hasnyálmirigy-veseátültetés--veseelégtelenséggel szövodött 1. típusú diabetes mellitus kezelésének alternatív módja.', Orvosi Hetilap, vol. 145, no. 24, pp. 1259-1264.
Kalmár Nagy, Károly ; Baumann, János ; Szakály, Péter ; Gyori Molnár, Iván ; Wittmann, I. ; Lodge, Peter ; Horváth Ors, Péter. / Kombinált hasnyálmirigy-veseátültetés--veseelégtelenséggel szövodött 1. típusú diabetes mellitus kezelésének alternatív módja. In: Orvosi Hetilap. 2004 ; Vol. 145, No. 24. pp. 1259-1264.
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AU - Baumann, János

AU - Szakály, Péter

AU - Gyori Molnár, Iván

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AU - Lodge, Peter

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