Simultaneous effect of salt and methanol concentrations on the hydrophobicity of some ion-pairing agents

Tibor Cserháti, Mariacarla Gennaro

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The lipophilicity (hydrophobicity) of some alkylamines and arylamines was determined with reversed-phase thin-layer chromatography using various water: methanol mixtures as eluent with and without adding salt to the system. The effect of various structural parameters of amines and that of the chromatographic conditions were assessed with stepwise regression analysis. The calculation proved that in case of alkylamines the lipophilicity does not depend linearly on the length of the alkyl chain, the effect of methanol and salt concentrations are intercorrelated and the influence of the alkyl chain branching is negligible. In case of arylamines the number of amino groups has the highest impact on the retention and the effect of methanol and salt is also intercorrelated.

Original languageEnglish
Pages (from-to)26-29
Number of pages4
JournalFresenius' Journal of Analytical Chemistry
Volume342
Issue number1-2
DOIs
Publication statusPublished - Jan 1 1992

ASJC Scopus subject areas

  • Biochemistry

Fingerprint Dive into the research topics of 'Simultaneous effect of salt and methanol concentrations on the hydrophobicity of some ion-pairing agents'. Together they form a unique fingerprint.

  • Cite this