Simultaneous activation of coagulation and fibrinolysis after severe renal ischemia in rats

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Coagulation and fibrinolysis were studied during and after bilateral renal artery occlusion for 2 h in rats. After the release of the arterial clamps platelet count and plasma fibrinogen concentration decreased and circulating fibrin monomers were detected. The shortening of euglobulin lysis time and the accumulation of fibrinogen/fibrin degradation products indicated a simultaneous activation of fibrinolysis. Rapid and severe hemolysis was evident by the steadily increasing plasma hemoglobin concentration. Bilateral nephrectomy reversed all these pathological changes.

Original languageEnglish
Pages (from-to)180-184
Number of pages5
JournalNephron
Volume32
Issue number2
Publication statusPublished - 1982

Fingerprint

Fibrinolysis
Ischemia
Fibrin Clot Lysis Time
Fibrin Fibrinogen Degradation Products
Kidney
Renal Artery
Hemolysis
Nephrectomy
Platelet Count
Fibrinogen
Hemoglobins
fibrinmonomer

ASJC Scopus subject areas

  • Nephrology

Cite this

Simultaneous activation of coagulation and fibrinolysis after severe renal ischemia in rats. / Losonczy, G.; Hársing, L.

In: Nephron, Vol. 32, No. 2, 1982, p. 180-184.

Research output: Contribution to journalArticle

@article{416a5b8ec6fc4359a45db68e544f16b1,
title = "Simultaneous activation of coagulation and fibrinolysis after severe renal ischemia in rats",
abstract = "Coagulation and fibrinolysis were studied during and after bilateral renal artery occlusion for 2 h in rats. After the release of the arterial clamps platelet count and plasma fibrinogen concentration decreased and circulating fibrin monomers were detected. The shortening of euglobulin lysis time and the accumulation of fibrinogen/fibrin degradation products indicated a simultaneous activation of fibrinolysis. Rapid and severe hemolysis was evident by the steadily increasing plasma hemoglobin concentration. Bilateral nephrectomy reversed all these pathological changes.",
author = "G. Losonczy and L. H{\'a}rsing",
year = "1982",
language = "English",
volume = "32",
pages = "180--184",
journal = "Experimental Nephrology",
issn = "0028-2766",
publisher = "S. Karger AG",
number = "2",

}

TY - JOUR

T1 - Simultaneous activation of coagulation and fibrinolysis after severe renal ischemia in rats

AU - Losonczy, G.

AU - Hársing, L.

PY - 1982

Y1 - 1982

N2 - Coagulation and fibrinolysis were studied during and after bilateral renal artery occlusion for 2 h in rats. After the release of the arterial clamps platelet count and plasma fibrinogen concentration decreased and circulating fibrin monomers were detected. The shortening of euglobulin lysis time and the accumulation of fibrinogen/fibrin degradation products indicated a simultaneous activation of fibrinolysis. Rapid and severe hemolysis was evident by the steadily increasing plasma hemoglobin concentration. Bilateral nephrectomy reversed all these pathological changes.

AB - Coagulation and fibrinolysis were studied during and after bilateral renal artery occlusion for 2 h in rats. After the release of the arterial clamps platelet count and plasma fibrinogen concentration decreased and circulating fibrin monomers were detected. The shortening of euglobulin lysis time and the accumulation of fibrinogen/fibrin degradation products indicated a simultaneous activation of fibrinolysis. Rapid and severe hemolysis was evident by the steadily increasing plasma hemoglobin concentration. Bilateral nephrectomy reversed all these pathological changes.

UR - http://www.scopus.com/inward/record.url?scp=0019920325&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019920325&partnerID=8YFLogxK

M3 - Article

C2 - 7177295

AN - SCOPUS:0019920325

VL - 32

SP - 180

EP - 184

JO - Experimental Nephrology

JF - Experimental Nephrology

SN - 0028-2766

IS - 2

ER -