Simulation of the temperature increase in human cadaver retina during direct illumination by 150-kHz femtosecond laser pulses

Hui Sun, Nora Hosszufalusi, Eric R. Mikula, Tibor Juhasza

Research output: Contribution to journalArticle

12 Citations (Scopus)


We have developed a two-dimensional computer model to predict the temperature increase of the retina during femtosecond corneal laser flap cutting. Simulating a typical clinical setting for 150-kHz iFS advanced femtosecond laser (0.8- to 1-μJ laser pulse energy and 15-s procedure time at a laser wavelength of 1053 nm), the temperature increase is 0.2°C. Calculated temperature profiles show good agreement with data obtained from ex vivo experiments using human cadaver retina. Simulation results obtained for different commercial femtosecond lasers indicate that during the laser in situ keratomileusis procedure the temperature increase of the retina is insufficient to induce damage.

Original languageEnglish
Article number108001
JournalJournal of Biomedical Optics
Issue number10
Publication statusPublished - Oct 1 2011



  • biomedical optics
  • laser applications
  • laser in situ keratomileusis
  • lasers in medicine
  • ophthalmology
  • thermal effect

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Biomedical Engineering

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